CD45 (PTPRC) Mouse Monoclonal Antibody [Clone ID: LBI1E1]

CD45 (PTPRC) Mouse Monoclonal

Antibody [Clone ID: LBI1E1]
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  • ¥653 - 2700
  • Leading Biology
  • 美国
  • 2025年07月10日
  • IHC 1:16000
  • Mouse
  • Human
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    • 详细信息
    • 技术资料
    • 靶点

      PTPRC

    • 浓度

      1 mg/ml

    • 应用范围

      IHC 1:16000

    • 宿主

      Mouse

    • 适应物种

      Human

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

    • 亚型

      IgG2b

    • 免疫原

      Human recombinant protein fragment corresponding to amino acids 931-1165 of human CD45 (NP_002829) produced in E.coli.

    • 规格

      100 ul/30 ul

    规格:100 ul产品价格:¥2700.0
    规格:30 ul产品价格:¥653.0
    别名:B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200

    产品概述:CD45 mouse monoclonal antibody, clone LBI1E1

    总结:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

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