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MedChemExpress LLC
- CAS号:
1031993-35-7
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询盘
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A1AR antagonist 4
CAS No. : 1031993-35-7
MCE 国际站:A1AR antagonist 4
产品活性:A1AR antagonist 4 (化合物 22) 是一种有效的选择性的 A1AR (A1 腺苷受体)拮抗剂,其 pIC50 为 5.51,pKi 为 6.29。
研究领域:GPCR/G Protein
作用靶点:Adenosine Receptor
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文献和实验Ligand Characterization Using Microphysiometry
the use of a Cytosensor microphysiometer for functional characterization of an agonist and antagonist to a G protein?coupled receptor, the muscarinic M1 receptor. Concentration?response profiles are used to calculate values for the EC50 of the response
Characterization of Chemokine Receptors
Assay Using Scintillation Proximity Assay (SPA) Technology on Membranes Expressing a Chemokine Receptor Alternate Protocol 1: SPA‐Based [35S]GTPγS Binding to Cell Membranes Expressing Chemokine Receptors
Practical Aspects of Radioligand Binding
Figure 1.3.3 Competition between a radiolabeled antagonist and an unlabeled agonist for muscarinic receptors on N1E‐115 cells. [3 H]Quinuclidinyl benzilate ([3 H]QNB; 0.2 nM) was incubated with 200,000 intact cells/tube and various concentrations
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