- ￥815
- 翌圣生物（Yeasen）
- 上海翌圣
- 92803ES10
- 2025年10月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
有效期1年
- 保存条件：
-20℃至-80℃保存
- 英文名：
Recombinant Human Parathyroid Hormone-related Protein (Human PTHrP)
- 库存：
大量
- 供应商：
翌圣生物科技（上海）股份有限公司
- 规格：
10μg
Product Information
|
Product Name |
Cat# |
Size |
Price（¥） |
|
Recombinant Human Parathyroid Hormone-related Protein (Human PTHrP) |
92803ES10 |
10 μg |
815.00 |
|
92803ES60 |
100 μg |
3985.00 |
|
|
92803ES76 |
500 μg |
10215.00 |
Product Description
PTHrP, also named parathyroid hormone-related protein, is belonging to the parathyroid hormone family. PTHrP is expressed in cancer cells (breast cancer, certain types of lung cancer including squamous cell lung carcinoma). The receptor for PTHrP is PTHR1. PTHrP plays a central role in regulating the hypercalcemia. Recombinant human PTHrP is a 9.9 kDa linear polypeptide of 86 amino acid residues and it shares 86 % a.a. identity with mouse PTHLH.
Product Properties
|
Synonyms |
Parathormone, Parathyrin |
|
Accession |
|
|
GeneID |
|
|
Source |
E.coli-derived human PTHrP protein, Ala37-Pro122. |
|
Molecular Weight |
Approximately 9.9 kDa. |
|
AA Sequence |
AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTP |
|
Tag |
None |
|
Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
|
Purity |
>98% by SDS-PAGE and HPLC analyses. |
|
Biological Activity |
Testing in progress. |
|
Endotoxin |
< 0.1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in 10 mM PB, pH 6.0, 300 mM NaCl. |
|
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only!
HB220510
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文献和实验上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人甲状旁腺素相关肽 ( PTHrP )ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 PTHrP 单抗包被于酶标板上，标准品和样品中的 PTHrP与单抗结合，加入生物素化的抗人
greatlj1211 请问各位大侠：IHH/PTHrP信号通路中IHH（indian hedgehog）翻译成中文因该是什么啊?万分感激！ 螺旋 甲状旁腺素相关肽（PTHrp）-印第安刺猬蛋白（Ihh）信号轴是骨骺生长板中调节软骨和成骨细胞增殖、分化、肥大和矿化的重要负反馈轴。围绕该信号轴有多种生长因子如Sox9、BMP、TGF-β等，参与调控软骨及成骨细胞生长。新近研究表明，PTHrp通过Sox9阻止软骨前体细胞向肥大
。PTH主要在肝水解灭活，代谢产物经肾排出体外。 近年从鳞状上皮癌伴发高血钙的患者癌组织中，分离出一种在化学结构上类似PTH的肽，称为甲状旁腺激素相关(parathyroid hormone related peptide,PTHrp)，并进一步发现正常组织如皮肤、乳腺以及胎儿甲状旁腺中也存在这种肽。PTHrp与PTH从来源上是同族的，尤其两者的N端1-13位氨基酸残其完全相同，PTHrp也具有PTH活性。 （一）甲状旁腺激素的生物学作用 PTH是调节血钙水平的最重要激素
