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- 保存条件:
-20°C, protect from light, stored under nitrogen
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
100 μg
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DM4-d6
MCE 国际站:DM4-d6
产品活性:DM4-d6 是 DM4 氘代物。DM4 是抑制细胞分裂的抗微管蛋白剂。DM4 可用于制备抗体活性分子偶联物。
研究领域:Others | Cell Cycle/DNA Damage | Cytoskeleton | Antibody-drug Conjugate/ADC Related
作用靶点:Isotope-Labeled Compounds | Microtubule/Tubulin | ADC Cytotoxin
In Vitro: Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
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文献和实验人CYP2D6 酶联免疫分析 试剂盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆及相关液体样本中 CYP2D6 的含量。 实验原理: 本试剂盒应用双抗体夹心法测定标本中人 CYP2D6 水平。用纯化的人 CYP2D6 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入 CYP2D6 ,再与 HRP 标记的 CYP2D6 抗体结合,形成抗体 - 抗原 - 酶标抗体复合物,经过彻底洗涤
Genotyping for Functionally Important Human CYP2D6*4 (B) Mutation Using TaqMan Probes
The microsomal enzyme cytochrome P450 2D6 (CYP2D6), also known as debrisoquine 4-hydroxylase, is involved in the oxidative metabolism of many widely used drugs, including neuroleptics, tricyclic antidepressants, antiarrhythmics, and β
A reverse-phase, high-performance liquid chromatography method is described for the quantification of 1′-hydroxybufuralol formed enzymatically by the incubation of bufuralol with cDNA-expressed CYP2D6 or human liver microsomes. Analytical
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