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Urease-IN-2
MCE 国际站:Urease-IN-2
产品活性:Urease-IN-2 (compound 8g) 是一种非竞争性脲酶 (urease) 抑制剂,IC50 为 0.94 μM,Ki 为 1.6 μM。Urease-IN-2 以非竞争性方式抑制 Jack bean 豆脲酶 (JBU)。
研究领域:Anti-infection
作用靶点:Bacterial
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文献和实验酰胺酶之一,为催化尿素水解的酶, EC3. 5. 1. 5。 CO( NH2 ) 2 + H2 O—→ 2NH3 CO2 在细菌、霉菌、高等植物(特别是豆科植物)、低等动物、哺乳类的胃粘膜、红血球等中可以找到。红血球中的脲酶可被血清中的某种物质和重金属、氟化物、卤素、硼酸盐、醌、 H2 O2 、 SH试剂所抑制,而还原剂、氰酸、蛋白质、亲水胶体则具有保护作用。萨姆纳( J. B. Sumner, 1926)曾从刀豆中获得了它的结晶,这是首次
Detection of H. pylori Infection by Biopsy Urease, Histology, and Culture
Detection of Helicobacter pylori in specimens obtained by endoscopy requires the gastroenterologist to select suitable patients for endoscopy, and to take an adequate number of biopsy specimens; there must also be correct cleaning
, which may be of interest to metabolic physicians and biochemical geneticists. By replacing the traditional extraction step with an enzymatic treatment of the sample with urease, an abundance of organic molecules are available for separation and quantitation by GC-MS. The urease method
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