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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
CCND2
- 浓度:
1 mg/ml
- 应用范围:
WB 1:2000
- 宿主:
Mouse
- 适应物种:
Human, Mouse, Rat
- 保质期:
1-2年
- 供应商:
安诺伦(北京)生物科技有限公司
- 标记物:
Unconjugated
- 克隆性:
Monoclonal Antibody
- 保存条件:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态:
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
- 亚型:
IgG2b
- 免疫原:
Full length human recombinant protein of human CCND2 (NP_001750) produced in E.coli.
- 规格:
100 ul/30 ul
| 规格: | 100 ul | 产品价格: | ¥2025.0 |
|---|---|---|---|
| 规格: | 30 ul | 产品价格: | ¥690.0 |
产品概述:CCND2 mouse monoclonal antibody, clone LBI10E11
总结:The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. [provided by RefSeq, Oct 2008]
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文献和实验Immunodetection of cyclin D1 and D2/D3 using flow cytometry
-4326) or cyclin D2/D3 (cat. no. 14711A, clone G107-22). Other cyclin antibodies may be appropriate as well. Cy5-conjugated anti-mouse IgG (Jackson ImmunoResearch and Caltag) 0.5% paraformaldehyde in PBS 80% EtOH in ddH20 (stored at -20°C) cyclin
Immunodetection of cyclin D1 and D2/D3 using 488/630 nm dual laser flow cytometr(图)
D2/D3 (cat. no. 14711A, clone G107-22). Other cyclin antibodies may be appropriate as well. Cy5-conjugated anti-mouse IgG (Jackson ImmunoResearch and Caltag) 0.5% paraformaldehyde in PBS 80% EtOH in ddH20 (stored at -20℃) cyclin staining
Immunodetection of cyclin D1 and D2/D3 using 488/630 nm dual laser flow cytometry
against cyclin D1 (Pharmingen cat. no. 14561A, clone G12-4326), cyclin D2 /D3 (cat. no. 14711A, clone G107-22) and cyclin E, and is based on protocols originally designed by Z. Darzynkiewicz and colleagues. Although FITC-conjugated secondary or direct FITC
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