PD1 (PDCD1) (NM_005018) Human

产品概述：Purified recombinant protein of Homo sapiens programmed cell death 1 (PD1/PDCD1), residues 25-167aa, with C-terminal Fc tag, expressed in HEK293 cells. 蛋白长度：A DNA sequence from GoldORF clone, [GH40185V], encoding the extracellular domain (Leu25 - Gln167) of human programmed cell death 1 (PD1) 表达系统：HEK293 种属：Human 标签类型：C-Fc 分子量：41 通用名：PDCD1 总结：Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：PBS, pH7.4, 10% glycerol 别名：CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2