Sptlc1 (NM_009269) Mouse Recom

产品概述：Purified recombinant protein of Mouse serine palmitoyltransferase, long chain base subunit 1 (Sptlc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug 蛋白长度：A DNA sequence from Mouse cDNA ORF Clone, [GM36990V], encoding Mouse full-length Sptlc1. 表达系统：HEK293T 种属：Mouse 标签类型：C-MYC/DDK 分子量：53 kDa 通用名：Sptlc1 总结：Serine palmitoyltransferase (SPT) (PubMed:28100772). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates. The SPTLC1-SPTLC2-SPTSSB complex displays a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme has the ability to use a broader range of acyl-CoAs (By similarity). Required for adipocyte cell viability and metabolic homeostasis (PubMed:28100772).[UniProtKB/Swiss-Prot Function] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. 别名：AW552086; C77762; E030036H05; Lcb1