PARP1 (NM_001618) Human Recomb

产品概述：Recombinant protein of human poly (ADP-ribose) polymerase 1 (PARP1), full length, with C-terminal flag tag, expressed in sf9 cells 蛋白长度：A DNA sequence from GoldORF clone, [GH36980V], encoding human full-length PARP1 表达系统：Sf9 种属：Human 标签类型：C-DDK 分子量：113 kDa 通用名：PARP1 总结：This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：50mM Tris-HCl pH8.0, 150mM NaCl, 10%glycerol 别名：ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; PPOL