产品概述:Recombinant protein of human poly (ADP-ribose) polymerase 1 (PARP1), full length, with C-terminal flag tag, expressed in sf9 cells蛋白长度:A DNA sequence from GoldORF clone, [GH36980V], encoding human full-length PARP1表达系统:Sf9种属:Human标签类型:C-DDK分子量:113 kDa通用名:PARP1总结:This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]形式:Liquid浓度:>50 ug/mL as determined by microplate BCA method纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining储存溶液:50mM Tris-HCl pH8.0, 150mM NaCl, 10%glycerol别名:ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; PPOL