- $3215
- Leading Biology
- 美国
- PH50509I6
- 2025年07月12日
10 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -529°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
50 ug
蛋白长度：A DNA sequence encoding the human MAPK12 (P53778) (Met1-Leu367) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
性质：
表达系统：Baculovirus-Insect Cells
种属：Human
氨基酸序：Met1-Leu367
标签类型：N-GST & His
分子量：The recombinant human MAPK12 /GST chimera consists of 604 amino acids and has a calculated molecular mass of 69.8 kDa. The recombinant protein migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
活性：Kinase activity untested
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：mitogen-activated protein kinase 12
通用名：MAPK12
蛋白序参考：
总结：ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/threonine kinase that acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 2 to 3 substrates each. MAPK12 is required for the normal kinetochore localization of PLK1, prevents chromosomal instability, and supports mitotic cell viability. MAPK12-signaling is also positively regulating the expansion of transient amplifying myogenic precursor cells during muscle growth and regeneration.
形式：Liquid
纯度：> 95 % as determined by SDS-PAGE.
储存条件：Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Supplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA.
别名：ERK-6 Protein, Human; ERK3 Protein, Human; ERK6 Protein, Human; MAPK12 Protein, Human; P38GAMMA Protein, Human; PRKM12 Protein, Human; SAPK-3 Protein, Human; SAPK3 Protein, Human
性质：
表达系统：Baculovirus-Insect Cells
种属：Human
氨基酸序：Met1-Leu367
标签类型：N-GST & His
分子量：The recombinant human MAPK12 /GST chimera consists of 604 amino acids and has a calculated molecular mass of 69.8 kDa. The recombinant protein migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
活性：Kinase activity untested
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：mitogen-activated protein kinase 12
通用名：MAPK12
蛋白序参考：
总结：ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/threonine kinase that acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 2 to 3 substrates each. MAPK12 is required for the normal kinetochore localization of PLK1, prevents chromosomal instability, and supports mitotic cell viability. MAPK12-signaling is also positively regulating the expansion of transient amplifying myogenic precursor cells during muscle growth and regeneration.
形式：Liquid
纯度：> 95 % as determined by SDS-PAGE.
储存条件：Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Supplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA.
别名：ERK-6 Protein, Human; ERK3 Protein, Human; ERK6 Protein, Human; MAPK12 Protein, Human; P38GAMMA Protein, Human; PRKM12 Protein, Human; SAPK-3 Protein, Human; SAPK3 Protein, Human
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
P38 Gamma/MAPK12 Protein, Human, Recombinant (His & GST Tag)
$3215
