产品概述:Purified recombinant protein of Human POU class 5 homeobox 1 (POU5F1/OCT4), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug蛋白长度:A DNA sequence encoding human full-length POU5F1/OCT4表达系统:E. coli种属:Human标签类型:N-His分子量:21.1 kDa通用名:POU5F1总结:This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]形式:Liquid浓度:>50 ug/mL as determined by microplate BCA method纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining储存溶液:25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.别名:Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4