MUM1 (IRF4) (NM_002460) Human

产品概述：Purified recombinant protein of Human interferon regulatory factor 4 (IRF4), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug 蛋白长度：A DNA sequence encoding human full-length IRF4 表达系统：E. coli 种属：Human 标签类型：N-GST and C-His 分子量：79.6 kDa 通用名：IRF4 总结：The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl. 别名：LSIRF; MUM1; NF-EM5; SHEP8