产品概述:Purified recombinant protein of Human SECIS binding protein 2 (SECISBP2), Met1-Gln101, with N-terminal His-PDCD1(Pro21-Val170) tag, expressed in E. coli, 50ug蛋白长度:A DNA sequence encoding the region(Met1-Gln101) of SECISBP2表达系统:E. coli种属:Human标签类型:N-terminal His-PDCD1(Pro21-Val170) tag分子量:27.9 kDa通用名:SECISBP2总结:The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]形式:Liquid浓度:>50 ug/mL as determined by microplate BCA method纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining储存溶液:50mM Tris, 8M Urea, pH8.0别名:SBP2