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- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -1329°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
1 mg
蛋白长度：A DNA sequence encoding the extracellular domain (Met 1-Pro 250) of human erythropoietin receptor (NP_000112.1) precursor was fused with a polyhistidine tag at the C-terminus.
性质：
表达系统：HEK293 Cells
种属：Human
氨基酸序：Met1-Pro250
标签类型：C-His
分子量：The secreted recombinant human EPOR consists of 237 amino acids and has a predicted molecular mass of 26.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhEPOR is approximately 34 kDa due to glycosylation.
活性：Measured by its ability to inhibit EPO-dependent proliferation of TF-1 human erythroleukemic cells.The EDfor this effect is typically 15-60 ng/mL in the presence of 0.1 U/mL Recombinant Human EPO.
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：erythropoietin receptor
通用名：EPOR
蛋白序参考：NP_000112.1
总结：Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type a… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
形式：Lyophilized
纯度：> 98 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, 0.05% CHAPS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：EPO-R Protein, Human
性质：
表达系统：HEK293 Cells
种属：Human
氨基酸序：Met1-Pro250
标签类型：C-His
分子量：The secreted recombinant human EPOR consists of 237 amino acids and has a predicted molecular mass of 26.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhEPOR is approximately 34 kDa due to glycosylation.
活性：Measured by its ability to inhibit EPO-dependent proliferation of TF-1 human erythroleukemic cells.The EDfor this effect is typically 15-60 ng/mL in the presence of 0.1 U/mL Recombinant Human EPO.
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：erythropoietin receptor
通用名：EPOR
蛋白序参考：NP_000112.1
总结：Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type a… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
形式：Lyophilized
纯度：> 98 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, 0.05% CHAPS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：EPO-R Protein, Human
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EPOR Protein, Human, Recombinant (ECD, His Tag)
$15000
