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ALK Rat Monoclonal Antibody [C

lone ID: LBI3E7]
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  • ¥3300
  • Leading Biology
  • 美国
  • 2025年07月14日
  • WB 1:2000
  • Rat
  • Human, Mouse, Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 靶点

      ALK

    • 应用范围

      WB 1:2000

    • 宿主

      Rat

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

    • 亚型

      IgG1

    • 免疫原

      Full length human recombinant protein of human ALK (NP_004295) produced in HEK293T cell.

    • 规格

      100 ug

    别名:CD246; NBLST3

    产品概述:Carrier-free (BSA/glycerol-free) ALK rat monoclonal antibody, clone LBI3E7

    总结:This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). [provided by RefSeq, Jan 2011]

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    图标文献和实验
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