![SMC1 (SMC1A) Mouse Monoclonal Antibody [Clone ID: LBI3G4]](https://img1.dxycdn.com/2022/0707/344/1496323853485278553-14.jpg)
- ￥3300
- Leading Biology
- AMM19235VCF
- 美国
- 2025年07月13日
- WB 1:500, IHC 1:500
- Mouse
- Human, Mouse, Rat
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- 详细信息
- 技术资料
- 靶点：
SMC1A
- 应用范围：
WB 1:500, IHC 1:500
- 宿主：
Mouse
- 适应物种：
Human, Mouse, Rat
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 标记物：
Unconjugated
- 克隆性：
Monoclonal Antibody
- 保存条件：
Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态：
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
- 亚型：
IgG1
- 免疫原：
Human recombinant protein fragment corresponding to amino acids 889-1016 of human SMC1A (NP_006297) produced in E.coli.
- 规格：
100 ug
别名：CDLS2; DXS423E; SB1.8; SMC1; SMC1alpha; SMC1L1; SMCB
产品概述：Carrier-free (BSA/glycerol-free) SMC1A mouse monoclonal antibody,clone LBI3G4
总结：Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
产品概述：Carrier-free (BSA/glycerol-free) SMC1A mouse monoclonal antibody,clone LBI3G4
总结：Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
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SMC1 (SMC1A) Mouse Monoclonal Antibody [Clone ID: LBI3G4]
￥3300
