PVRL1 (NECTIN1) Mouse Monoclonal Antibody [Clone ID: LBI6F8]

PVRL1 (NECTIN1) Mouse Monoclon

al Antibody [Clone ID: LBI6F8]
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  • ¥3300
  • Leading Biology
  • 美国
  • 2025年07月11日
  • WB 1:2000, IHC 1:150, IF 1:100
  • Mouse
  • Human
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    • 详细信息
    • 技术资料
    • 靶点

      NECTIN1

    • 应用范围

      WB 1:2000, IHC 1:150, IF 1:100

    • 宿主

      Mouse

    • 适应物种

      Human

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

    • 亚型

      IgG1

    • 免疫原

      Full length human recombinant protein of human PVRL1(NP_002846) produced in HEK293T cell.

    • 规格

      100 ug

    别名:CD111; CLPED1; ED4; HIgR; HV1S; HVEC; nectin-1; OFC7; PRR; PRR1; PVRL1; PVRR; PVRR1; SK-12

    产品概述:Carrier-free (BSA/glycerol-free) PVRL1 mouse monoclonal antibody, clone LBI6F8

    总结:This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq]

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