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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide from the internal region of p53 which includes the mutation of R175H, human origin.
- 亚型:
IgG
- 形态:
液体
- 保存条件:
零下20℃
- 克隆性:
多克隆
- 标记物:
FITC
- 适应物种:
脊椎动物
- 保质期:
24个月
- 抗原来源:
蛋白
- 目录编号:
TD-21161
- 级别:
科研级
- 库存:
999
- 供应商:
武汉天德
- 宿主:
兔
- 应用范围:
ELISA, WB, IHC, IP
- 浓度:
0.1 mg/ml
- 靶点:
R175H
- 抗体英文名:
Anti TP53(R175H) Rabbit Polyclonal Antibody
- 抗体名:
TP53(R175H) Polyclonal Antibody
- 规格:
100μl
TP53(R175H) Polyclonal Antibody
| Cat. #: TD-21161 |
| Gene Symbol: TP53(R175H) |
| Description: Anti-TP53(R175H) Rabbit Polyclonal Antibody |
| Background: p53 protein acts as a tumor suppressor in many tumor types and induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Defects in TP53 are found in many types of cancers. |
| Immunogen: A synthetic peptide from the internal region of p53 which includes the mutation of R175H, human origin. |
| Applications: ELISA, WB, IHC, IP |
| Recommended Dilutions: ELISA: 1:100-1:5000 WB: 1:100-1:2000 IHC: 1:50-1:100 |
| Concentration: 0.1 mg/ml |
| Host Species: Rabbit |
| Format: : Liquid |
| Clonality: Polyclonal |
| Isotype: |
| Purity: Purified from serum |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-TP53(R175H) antibody recognizes TP53(R175H) of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇:make an Antibody against a Peptides 下一篇:Immunization Protocol for Monoclonal Antibody Production
Science:直击肿瘤命门,Shibin Zhou 等开发靶向 TP53 突变的双特异性抗体
p53-targeted immunotherapyEurekAlert Science NewsR175H,其中 175 位的精氨酸被组氨酸取代,是 TP53 中观察到的最常见的突变,也是任何肿瘤抑制基因中最常见的突变。HMTEVVRHC (带下划线的为突变氨基酸) 来源于 p53R175H,与人类白细胞抗原 (HLA) 等位基因 (A*02:01) 结合,该等位基因存在于超过 40% 的美国高加索人中。近年来,TCR-Mimic (TCRm) 抗体已成为一类靶向肿瘤细胞内蛋白 pHLA(多肽 - MHC 复合
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
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