- ￥4800
- Tanda
- 美国
- TD-26329
- 2026年01月23日
- ELISA, WB, IHC
- Mouse
- 脊椎动物
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide from the internal region of GNAQ which includes the mutation of Q209P, human origin.
- 亚型：
IgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
单克隆
- 标记物：
FITC
- 适应物种：
脊椎动物
- 保质期：
24个月
- 抗原来源：
蛋白
- 目录编号：
TD-26329
- 级别：
科研级
- 库存：
999
- 供应商：
武汉天德
- 宿主：
Mouse
- 应用范围：
ELISA, WB, IHC
- 浓度：
1mg/ml
- 靶点：
Q209P
- 抗体英文名：
Anti GNAQ(Q209P) Mouse Monoclonal Antibody
- 抗体名：
Gαq(Q209P)
- 规格：
100μl
Gαq(Q209P)
| Cat. #: TD-26329 |
| Gene Symbol: GNAQ, CMC1, G-ALPHA-q, GAQ, SWS |
| Description: Anti-GNAQ(Q209P) Mouse Monoclonal Antibody |
| Background: GNAQ is a protein that in humans encoded by the GNAQ gene. The GNAQ protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospholipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. |
| Immunogen: A synthetic peptide from the internal region of GNAQ which includes the mutation of Q209P, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes Gαq(Q209P) mutant, but not wild type GNAQ of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
|
Western blot:
Western blot analysis of recombinant GNAQ(Q209P) and wild type proteins. Purified His-tagged GNAQ(Q209P) protein (lane2) and corresponding wild type protein (lane1) were blotted with Anti-GNAQ(Q209P) monoclonal antibody (Cat. #TD-26329). Immunofluorescence::
Immunofluorescence of cells expressing GNAQ proteins with Anti-GNAQ(Q209P) antibody. HEK293T cells were transfected with pCDNA3-GFP-GNAQ(Q209P) plasmid, pCDNA3-GFP-GNAQ (WT) plasmid, pCDNA3-GFP-GNAQ (Q209L) plasmid or pCDNA3-GFP-GNAQ (Q209R) plasmid, then fixed and stained with Anti-GNAQ(Q209P) monoclonal antibody (Cat. #TD-26329). |
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文献和实验Identification and Quantitation of G-Protein α-Subunits
The demonstration that many intracellular signaling processes are mediated by a family of closely related guanine nucleotide binding proteins (G-proteins) has led to the development of specific techniques that can be used to identify
On activation, G-protein-coupled receptors (GPCRs) exert many of their cellular actions through promotion of guanine nucleotide exchange on the Gα-subunit of heterotrimeric G-proteins to release free Gα-GTP and βγ-subunits. In membrane
砷剂疗法的前世今生：「吃最毒的药，治最难的病」，「砒霜」抗癌再登 Cell 子刊
1061., 1996.[5] J. Mervis, Ancient Remedy Performs New Tricks, Science, 1996.[6] X.-G. S. W. T. S.-M. X. J. Z. X. C. Z.-G. H. J.-H. N. G.-Y. S. P.-M. J. M.-M. L. K.-L. H. C. N. J. M. P. Z. T.-D. Z. P. P. T. N. K. K. W. M. Guo-Qiang Chen, Use of Arsenic
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