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- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide from the internal region of β-catenin which includes the mutation of G38D, human origin.
- 亚型:
IgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
单克隆
- 标记物:
FITC
- 适应物种:
脊椎动物
- 保质期:
24个月
- 抗原来源:
蛋白
- 目录编号:
TD-26169
- 级别:
科研级
- 库存:
999
- 供应商:
武汉天德
- 宿主:
Mouse
- 应用范围:
ELISA, WB, IF, IHC
- 浓度:
1mg/ml
- 靶点:
G38D
- 抗体英文名:
Antiβ-catenin(G38D) Mouse Monoclonal Antibody
- 抗体名:
β-Catenin(G38D)
- 规格:
100μl
β-Catenin(G38D)
| Cat. #: TD-26169 |
| Gene Symbol: CTNNB1, CTNNB |
| Description: Anti-β-catenin(G38D) Mouse Monoclonal Antibody |
| Background: Beta-catenin(or β-catenin) is a protein that in humans is encoded by the CTNNB1 gene. β-catenin is a subunit of the cadherin protein complex and also acts as an intracellular signal transducer in the Wnt signaling pathway. Deregulation of beta-catenin signaling is an important event in the genesis of a number of malignancies, such as colon cancer, melanoma, hepatocellular carcinoma, ovarian cancer, endometrial cancer, medulloblastoma pilomatricomas, and prostate cancer. |
| Immunogen: A synthetic peptide from the internal region of β-catenin which includes the mutation of G38D, human origin. |
| Applications: ELISA, WB, IF, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:2000 IHC: 1:50-100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes β-catenin(G38D), but not wild type β-catenin protein from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
![]() Immunofluorescence: ![]() |
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文献和实验医生和球 看的文献较少,自己知道的只有wnt、PTEN等,请问还有哪些通路与β-catenin有关,有无类似的综述?谢谢! 狐狸renart 只知道wnt chuckdouble The canonical Wnt/beta-catenin signalling pathway. Barker N. Methods Mol Biol. 2008;468:5-15
【求助】关于β-catenin和细胞增殖的关系,急死了!!!
rainbubu 想研究β-catenin在某肿瘤中和细胞增殖和预后的关系,材料用存档的蜡块和冰冻,想用免疫组化来检测β-catenin的表达情况,然后想检测β-catenin的表达和细胞增殖的关系,能不能简单的看β-catenin和PCNA、ki-67之间的关系,有统计学意义就得出β-catenin和细胞增殖有相关性。 但是也不能说明细胞增殖就是β-catenin表达异常的结果啊 那么怎么才能说明β-catenin和细胞增殖的关系
liqiuling 怎么才能获取beta catenin的基因? chuckdouble pubmed里面有Nucleotide.到那里找. liqiuling 不太会看,而且合成的话,很贵,想知道如果想获得别人的惠赠,该怎样做?哪位大侠支个招?不胜感激! lmnsmu 在NCBI的核酸库中找到其序列,然后设计引物,通过RT-PCR扩增获得该基因
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