β-Catenin(G38D)

β-Catenin(G38D)

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  • ¥4800
  • Tanda
  • 美国
  • TD-26169
  • 2025年12月10日
  • ELISA, WB, IF, IHC
  • Mouse
  • 脊椎动物
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    • 详细信息
    • 技术资料
    • 免疫原

      A synthetic peptide from the internal region of β-catenin which includes the mutation of G38D, human origin.

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      -20℃

    • 克隆性

      单克隆

    • 标记物

      FITC

    • 适应物种

      脊椎动物

    • 保质期

      24个月

    • 抗原来源

      蛋白

    • 目录编号

      TD-26169

    • 级别

      科研级

    • 库存

      999

    • 供应商

      武汉天德

    • 宿主

      Mouse

    • 应用范围

      ELISA, WB, IF, IHC

    • 浓度

      1mg/ml

    • 靶点

      G38D

    • 抗体英文名

      Antiβ-catenin(G38D) Mouse Monoclonal Antibody

    • 抗体名

      β-Catenin(G38D)

    • 规格

      100μl

    β-Catenin(G38D)

    Cat. #:  TD-26169
    Gene Symbol:  CTNNB1, CTNNB
    Description:   Anti-β-catenin(G38D) Mouse Monoclonal Antibody
    Background:   Beta-catenin(or β-catenin) is a protein that in humans is encoded by the CTNNB1 gene. β-catenin is a subunit of the cadherin protein complex and also acts as an intracellular signal transducer in the Wnt signaling pathway. Deregulation of beta-catenin signaling is an important event in the genesis of a number of malignancies, such as colon cancer, melanoma, hepatocellular carcinoma, ovarian cancer, endometrial cancer, medulloblastoma pilomatricomas, and prostate cancer.
    Immunogen:   A synthetic peptide from the internal region of β-catenin which includes the mutation of G38D, human origin.
    Applications:   ELISA, WB, IF, IHC
    Recommended Dilutions:    ELISA: 1:1000-1:5000 WB: 1:500-1:2000 IHC: 1:50-100
    Concentration:   1 mg/ml
    Host Species:   Mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   IgG
    Purity:    Purified from ascites
    Preservative: No
    Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Recognizes β-catenin(G38D), but not wild type β-catenin protein from vertebrates.
    Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing
    Western blot: 
     β-Catenin(G38D)
    Western blot analysis of recombinant β-catenin(G38D) and wild type proteins. Purified His-tagged β-catenin(G38D) protein (amino acids 1-76, lane 2) and corresponding wild type protein (lane 1) were blotted with anti-β-catenin(G38D) mouse monoclonal antibody (Cat. #TD-26169). 
    Immunofluorescence:  
     β-Catenin(G38D)
    Immunofluorescence of cells expressing β-catenin proteins with anti-β-catenin(G38D) antibody. HEK293T cells were transfected with pCDNA3-GFP-CTNNB1 (WT) plasmid (left column) or pCDNA3-GFP-CTNNB1(G38D) plasmid (right column), then fixed and stained with anti-β-catenin(G38D) monoclonal antibody (Cat. #TD-26169).



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