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Anti-IL-17RB
IL-17RB抗体
详询
兔
/
见产品详情
IgG
冻干或液体
见产品详情
-20℃
1mg/ml
详询
英文名称 Anti-IL-17RB |
中文名称 白介素-17B受体抗体 |
别 名 IL17B Receptor; Interleukin-17 receptor B; IL17RB; CRL 4; CRL4; Cytokine receptor CRL4; EVI 27; EVI27; IL 17 receptor B; IL 17 receptor homolog 1; IL 17B receptor; IL 17RB; IL 17Rh1; IL17BR; IL17RH1; Interleukin 17 receptor B; Interleukin 17 receptor homolog 1; Interleukin 17 receptor homolog; Interleukin 17B receptor; ecotropic viral integration site 27; interleukin-17 receptor B precursor; MGC5245; I17RB_MOUSE. |
浓 度 1mg/1ml |
规 格 0.1ml/100μg 0.2ml/200μg |
抗体来源 Rabbit |
克隆类型 polyclonal |
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse |
产品类型 一抗 |
研究领域 免疫学 细胞膜受体 |
蛋白分子量 predicted molecular weight: 54kDa |
性 状 Lyophilized or Liquid |
免 疫 原 KLH conjugated synthetic peptide derived from human IL-17RB (345-390aa) |
亚 型 IgG |
纯化方法 affinity purified by Protein A |
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 |
(石蜡切片需做抗原修复) |
not yet tested in other applications. |
optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq]. |
Function : Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. |
Subunit : Interacts with DAZAP2. |
Subcellular Location : Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. |
Tissue Specificity : Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines. |
Similarity : Contains 1 SEFIR domain. |
Database links : |
UniProtKB/Swiss-Prot: Q9JIP3.1 |
Entrez Gene: 55540 Human |
Omim: 605458 Human |
SwissProt: Q9NRM6 Human |
Unigene: 5470 Human |
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