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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
详询
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-IFN gamma
- 抗体名:
IFN gamma抗体
- 标记物:
详询
- 宿主:
兔
- 适应物种:
/
- 免疫原:
见产品详情
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
见产品详情
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-IFN gamma |
| 中文名称 干扰素-γ/IFN-γ抗体 |
| 别 名 IFNG; IFG; IFI; IFN Gamma; IFN Immune; IFN-gamma; IFNG; IFNG_HUMAN; Immune Interferon; Interferon gamma; Interferon Gamma Precursor; Macrophage Activating Factor; MAF; T Cell Interferon; Type II Interferon. |
| 浓 度 1mg/1ml |
| 规 格 0.1ml/100μg 0.2ml/200μg 1ml/1mg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human |
| 产品类型 一抗 |
研究领域 肿瘤 免疫学 信号转导 干扰素 ![]() |
| 蛋白分子量 predicted molecular weight: 15kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human IFN Gamma C-terminus |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
| 保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ![]() |
| 产品介绍 Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2. |
| Function : Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| Subunit : Homodimer. |
| Subcellular Location : Secreted. |
| Tissue Specificity : Released primarily from activated T lymphocytes. |
| Post-translational modifications : Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. |
| DISEASE : In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis. |
| Similarity : Belongs to the type II (or gamma) interferon family. |
| Database links : |
| UniProtKB/Swiss-Prot: P01579.1 human |
| Entrez Gene: 3458 Human |
| Omim: 147570 Human |
| SwissProt: P01579 Human |
Unigene: 856 Human ![]() |
| Amylin(1-37) 糖尿病相关肽(胰岛淀粉样肽) |
| CCP peptide (cyclic citrullinated peptide,CCP) 瓜氨酸环肽 |
| CCP peptide (cyclic citrullinated peptide,CCP) 瓜氨酸环肽 |
| GLP-1(Glucagon-like peptide-1)(7-36) 胰高血糖素样肽-1(多肽) |
| GRGDS peptide 抗黏附多肽GRGDS |
| PACAP(1-38 Peptide) 腺苷酸环化酶激活肽 1-38(全蛋白) |
| MBP Antigen(Myelin Basic Protein, MBP) 髓鞘碱性蛋白(多肽抗原) |
| Leupeptin 亮抑酶肽 |
| GRP( Gastrin Releasing Peptide ) 促胃泌素释放肽(抗原) |
| YTA(标准) 牛血清白蛋白(标准) |
| MOG35-55 (myelin oligo-dendrocyte glycoprotein-MOG) 髓鞘少树突胶质细胞糖蛋白(抗原) |
| IGF-I( Insulin-like Growth Factor-I ) 胰岛素样生长因子-I(抗原) |
| VIP (Vasoactive Intestinal peptide) 血管活性肠肽 |
| IGF-II( Insulin-like Growth Factor-II ) 胰岛素样生长因子-II(抗原) |
| TP-5(Thymopentin) 胸腺五肽 |
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