- ￥1280 - 1980
- YLKBIO
- YLK-KT2216D
- 国产/进口
- 2025年07月08日
- WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 兔
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- 详细信息
- 技术资料
- 供应商：
优利科（上海）生命科学有限公司
- 库存：
100
- 靶点：
详询
- 级别：
科研
- 目录编号：
/
- 克隆性：
多克隆
- 抗原来源：
详见说明书
- 保质期：
1年
- 抗体英文名：
Anti-IGBP1
- 抗体名：
IGBP1抗体
- 标记物：
详询
- 宿主：
兔
- 适应物种：
/
- 免疫原：
KLH conjugated synthetic peptide derived from human Immunoglobulin binding protein 1
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 保存条件：
-20℃
- 浓度：
1mg/ml
- 规格：
详询
| 英文名称 Anti-IGBP1 |
| 中文名称 免疫球蛋白结合蛋白-1抗体 |
| 别 名 Alpha 4; B cell signal transduction molecule alpha 4; B-cell signal transduction molecule alpha 4; bA351K23.1; CD79a binding protein 1; CD79a-binding protein 1; IBP 1; IBP1; IGBP 1; Igbp1; IGBP1_HUMAN; Immunoglobulin (CD79A) binding protein 1; Immunoglobulin binding protein 1; Immunoglobulin-binding protein 1; Protein alpha 4; Protein alpha-4; Protein phosphatase 2A regulatory subunit alpha 4; Renal carcinoma antigen NY REN 16; Renal carcinoma antigen NY-REN-16. |
| 浓 度 1mg/1ml |
| 规 格 0.1ml/100μg 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Mouse, Rat, Pig, Cow, Guinea Pig |
| 产品类型 一抗 |
研究领域 肿瘤 细胞生物 免疫学 神经生物学 信号转导 激酶和磷酸酶  |
| 蛋白分子量 predicted molecular weight: 44kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human Immunoglobulin binding protein 1 |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| （石蜡切片需做抗原修复） |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.  |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways. [provided by RefSeq, Jul 2008]. |
| Function : Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of PP2A, PP4 and PP6 phosphatases catalytic subunits by protecting them from degradative polyubiquitination until they associate with regulatory subunits. |
| Subunit : Associates with PP2A-alpha and PP2A-beta catalytic subunits, and with PP4 and PP6. Interacts with MID1 and MID2. Interacts with Ubiquitin. |
| Subcellular Location : Cytoplasm (Potential). |
| Tissue Specificity : Ubiquitously expressed with highest levels in heart, skeletal muscle and pancreas. |
| Post-translational modifications : Phosphorylated. |
| Monoubiquitination by MID1 triggers calpain-mediated cleavage and switches IGBP1 activity from protective to destructive. |
| DISEASE : Mental retardation, X-linked, syndromic, 28 (MRXS28) [MIM:300472]: A mental retardation syndrome characterized by agenesis of the corpus callosum, coloboma of the iris and optic nerve, severe retrognathia, and intellectual deficit. Mental retardation is defined by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Note=The disease is caused by mutations affecting the gene represented in this entry. |
| Similarity : Belongs to the IGBP1/TAP42 family. |
| Contains 1 UIM (ubiquitin-interacting motif) repeat. |
| Database links : UniProtKB/Swiss-Prot: P78318 |
| CD79a表达于从前B细胞到浆细胞的整个B细胞发育阶段。 |
CD79a与CD79b构成B细胞受体复合体，在介导IgM从细胞内转到细胞膜上起重要作用。CD79a是B细胞常用标记物。CD79复合物是异二聚体分子，由CD79a/mb-1和CD79b/B29 组成。在B细胞表面非共价地与膜结合的免疫球蛋白相连，构成B细胞抗原受体。在大多数前B细胞急性淋巴细胞白血病、B细胞系、B细胞淋巴瘤和和某些骨髓瘤中发现有CD79a的存在。主要用于B淋巴细胞的判断和B细胞淋巴瘤的诊断。 |
| p21/WAF1/CIP1 p21 核分裂抑制因子之一（抗原） |
| p27 (cyclin-dependent kinase inhibitor 1B) p27(抗原) |
| P63 protein P63 肿瘤抑制基因（抗原） |
| OPG(Osteoprotegerin) 护骨素(多肽抗原) |
| OPGL (Osteoprotegerin ligand) 骨保护蛋白配体(抗原) |
| P311 protein 增生性瘢痕相关蛋白（抗原） |
| PARP(poly ADP-ribose polymerase) 多腺苷二磷酸多聚酶抗原 |
| Visfatin-1 (PBEF1)(NT) Human 内脂素/内脏脂肪素（人：N端多肽）、内脏脂肪素、 又称：前B细胞克隆增强因子、内肥素、腹脂素 |
| Visfatin-1 (PBEF1)(NT) hu、 mo、 rat、MK 内脂素/内脏脂肪素（人、大、小鼠、猴同源：N端多肽）、内脏脂肪素、前B细胞克隆增强因子、内肥素、腹脂素 |
| Visfatin-2(CT)hu、mo、rat、MK 内脂素/内脏脂肪素（抗人、大、小鼠、猴：N端多肽）前B细胞克隆增强因子、内肥素、腹脂素 |
| PEDF (pigment epithelium-derived factor) 色素上皮源性因子(多肽抗原） |
| PAP2c (Phosphatidic acid phosphatase 2c) 磷脂酸磷酸酶2C（抗原） |
| PEPT1 (Peptide-transporters 1) 肠道肽转运蛋白(小肽转运蛋白)多肽 |
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免疫球蛋白结合蛋白-1抗体
￥1280 - 1980
