- ￥4655.74
- Sigma-Aldrich
- L2630-100mg
- made in USA
- 2025年09月05日
11 年金牌会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 库存：
100⁺瓶
- 英文名：
LPS
- CAS号：
Sigma货号L2630-100mg
- 保质期：
1年
- 供应商：
上海睿安生物13611631389
- 保存条件：
2-8°C
- 规格：
100mg/瓶
现货Sigma货号L2630-100mg脂多糖LPS刺激先天性免疫系统细胞(规格包装100mg/瓶)(目录价¥4655.74元/瓶)13611631389上海睿安生物
一般描述
脂多糖(LPS)是革兰氏阴性菌细胞壁的特征组分。典型的LPS分子具有脂质A(一种基于葡糖胺的磷脂)、一个相对短的核心寡糖以及一个远端的多糖(O-抗原)。LPS有助于外膜的完整性，并可保护细胞免受胆汁盐和亲脂性抗生素的作用。它们通过TLR2和TLR4(toll样受体)对宿主细胞进行刺激。这种刺激可导致各种促炎细胞因子的生成，例如TNFα(肿瘤坏死因子)、IL-1(白细胞介素1)和IL-6。
该产品是从大肠杆菌血清型O111:B4中经酚抽提的。来源菌株来自私人收藏。该LPS血清型已用于刺激B细胞并在人肝细胞中诱导NOS(一氧化N合酶)。
应用:
来自大肠杆菌O111:B4的脂多糖(LPS)已用于巨噬细胞的刺激。它们在小鼠中已用于LPS的预处理。
脂多糖(LPS)是革兰氏阴性菌细胞壁的特征组分。LPS及其脂质A部分可通过能够识别常见的病原体相关分子模式(PAMP)的Toll样受体蛋白家族成员Toll样受体4(TLR4)刺激先天性免疫系统细胞。
包装:10mg，25mg，100mg in poly bottle
制备说明:
该产物可溶于水(5mg/ml)或细胞培养基(1mg/ml)，产生模糊的淡黄色溶液。以中更为浓缩但仍然模糊的溶液(20mg/ml)可形成于涡旋并升温至70-80°C后。脂多糖是在每种溶剂中都形成胶束的分子。在水和磷酸盐缓冲液中都能观察到模糊的溶液。有机溶剂也不会产生更为清澈的溶液。甲醇可产生具有漂浮物的混浊悬浮液，而水则能产生均匀模糊的溶液。
一、╳※试剂※╳:
常规血清优势供应:VivaCell货号C04001-500血清、Gemini货号900-108血清、Gemini血清、Gibco血清(10099-141澳洲血清、10270-106南美血清、16000-044血清)、BI血清BI货号04-001-1ACS、Sigma货号F8318-500ml澳洲胎牛血清、Sigma货号F8687澳洲胎牛血清、Sigma货号F2442-500ml特级胎牛血清、ScienCell货号0500澳洲胎牛血清、Cegrogen货号A0500-3010胎牛血清、Cegrogen货号B0500-5010新生牛血清、康源血清
培养基(包括无血清)、冻存液(包括无血清)，包括:友康Yocon
Merck(Millipore/Sigma/Roche/KaPa/Supelco/Avanti/Corning/Brand)正式授权代理、博奥龙Biodragon独家总代理、EFL独家总代理、碧云天Beyotime代理
☆☆☆☆☆☆Beckman货号A63881纯化磁珠Agencourt AMPure XP(60ml/瓶)/A63882(450ml/瓶)；Beckman货号B23317核酸片段筛选试剂盒Agencourt SPRIselect(5ml/瓶)
分子类:Biotium货号41003的GelRed染料、货号31000的EvaGreen染料、Zymo Research、Qiagen
饲料类:Research Diets、Dyets
二、╳※耗材※╳:
洁特JET耗材(各类常规用实验耗材)、赛普Cellpro耗材/KirGen耗材、博麦迪(常规的)各类试剂瓶
Bioplastics
Thermo Fisher Scientific的很多产品线，包括旗下的:
一、Nunc耗材
二、QSP耗材(各类吸头/滤芯吸头、离心管、PCR管等)
三、Nalgene耗材仪器
四、FisherBrand耗材仪器(含各类盖玻片载玻片等)
五、Lab_Serv耗材仪器
六、Finnpipette移液器(如：F1系列、F2系列、F3系列等等各类型号的移液器)
七、Abgene耗材
畅销款:我们是常备有大量现货的
可请随时咨询:万奎13611631389(可以请加微信)
※╳√√✓✔√✓✔√✓✔上海睿安生物科技有限公司成立于2009年，专注于为生命科学和生物技术领域的客户提供优质的产品与服务。代理了多家欧美知名品牌，如美国Thermo Fisher耗材(包括旗下Nunc、QSP、Nalgene、FisherBrand、Lab_Serv耗材仪器、Finnpipette移液器、Abgene耗材，等等)、默克Merck-Millipore/Sigma/Roche/KaPa/Supelco/Avanti/Corning/Brand)、Zymo Research、洁特JET耗材(各类常规用实验耗材)、赛普Cellpro耗材、博奥龙Biodragon独家总代理、EFL独家总代理、碧云天Beyotime代理、Eppendorf、友康Yocon、Research Diets高脂饲料，IBL、BioVendor、Mercodia、ShiBayaji代谢类产品、Axygen-Corning长期大量耗材备货、BioCaot畅销款长期备货，VivaCell血清、Gemini血清、Gibco血清，BI血清现货、ScienCell血清、Sigma血清、Moregate血清、Cegrogen血清、Pierce发光试剂、Fermentas、Invitrogen、Abcam、CST、BD、SAB、R&D systems、Beckman、Qiagen、BD Pharmingen、Biolegend、Jackson、Miltenyi、MP Biomedicals、Biotium更好的荧光试剂产品等品牌。睿安生物始终将“提供更好的产品和服务”作为企业发展的目标和努力的方向，并将通过优质的售前与售后服务，始终如一地为客户提供高质量的产品和服务，我们也希望能得到相关领域中更多老师和同仁们的指导和鞭策，为共创优秀品牌而努力奋斗！询订╳直线13611631389微信号
Jianbo Yu et al.
Anesthesiology, 125(6), 1190-1201 (2016-08-31)
Sepsis-associated acute lung injury remains the major cause of mortality in critically ill patients and is characterized by marked oxidative stress and mitochondrial dysfunction. Mitochondrial dynamics are indispensable for functional integrity. Additionally, heme oxygenase (HO)-1/carbon monoxide conferred cytoprotection against end-organ
Conserved gene regulation during acute inflammation between zebrafish and mammals.
G Forn-Cuní et al.
Scientific reports, 7, 41905-41905 (2017-02-06)
Zebrafish (Danio rerio), largely used as a model for studying developmental processes, has also emerged as a valuable system for modelling human inflammatory diseases. However, in a context where even mice have been questioned as a valid model for these
Outer membrane permeability and antibiotic resistance.
Delcour AH et al.
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 1794, 808-816 (2009)
Corticotropin-releasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice.
Agelaki S et al.
Infection and Immunity, 70, 6068-6068 (2002)
Systematic Identification and Analysis of Expression Profiles of mRNAs and Incrnas in Macrophage Inflammatory Response.
Lei Li et al.
Shock (Augusta, Ga.), 51(6), 770-779 (2018-12-19)
Long noncoding RNAs (lncRNAs), once thought to be transcriptional noise, have been recently shown to regulate a variety of biological processes. However, their roles in the inflammatory response are largely unexplored. In this study, we performed high-throughput sequencing to identify
同行评审论文
Heme Oxygenase-1/Carbon Monoxide-regulated Mitochondrial Dynamic Equilibrium Contributes to the Attenuation of Endotoxin-induced Acute Lung Injury in Rats and in Lipopolysaccharide-activated Macrophages.Jianbo Yu et al.
Anesthesiology, 125(6), 1190-1201 (2016-08-31)
Sepsis-associated acute lung injury remains the major cause of mortality in critically ill patients and is characterized by marked oxidative stress and mitochondrial dysfunction. Mitochondrial dynamics are indispensable for functional integrity. Additionally, heme oxygenase (HO)-1/carbon monoxide conferred cytoprotection against end-organ
Conserved gene regulation during acute inflammation between zebrafish and mammals.
G Forn-Cuní et al.
Scientific reports, 7, 41905-41905 (2017-02-06)
Zebrafish (Danio rerio), largely used as a model for studying developmental processes, has also emerged as a valuable system for modelling human inflammatory diseases. However, in a context where even mice have been questioned as a valid model for these
Outer membrane permeability and antibiotic resistance.
Delcour AH et al.
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 1794, 808-816 (2009)
Corticotropin-releasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice.
Agelaki S et al.
Infection and Immunity, 70, 6068-6068 (2002)
Systematic Identification and Analysis of Expression Profiles of mRNAs and Incrnas in Macrophage Inflammatory Response.
Lei Li et al.
Shock (Augusta, Ga.), 51(6), 770-779 (2018-12-19)
Long noncoding RNAs (lncRNAs), once thought to be transcriptional noise, have been recently shown to regulate a variety of biological processes. However, their roles in the inflammatory response are largely unexplored. In this study, we performed high-throughput sequencing to identify
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
- 作者
- 内容
- 询问日期
文献和实验该产品被引用文献
现货Sigma货号L2630-100mg脂多糖LPS刺激先天性免疫系统细胞(规格包装100mg/瓶)(目录价¥4655.74元/瓶)13611631389上海睿安生物
一般描述
脂多糖(LPS)是革兰氏阴性菌细胞壁的特征组分。典型的LPS分子具有脂质A(一种基于葡糖胺的磷脂)、一个相对短的核心寡糖以及一个远端的多糖(O-抗原)。LPS有助于外膜的完整性，并可保护细胞免受胆汁盐和亲脂性抗生素的作用。它们通过TLR2和TLR4(toll样受体)对宿主细胞进行刺激。这种刺激可导致各种促炎细胞因子的生成，例如TNFα(肿瘤坏死因子)、IL-1(白细胞介素1)和IL-6。
该产品是从大肠杆菌血清型O111:B4中经酚抽提的。来源菌株来自私人收藏。该LPS血清型已用于刺激B细胞并在人肝细胞中诱导NOS(一氧化N合酶)。
应用:
来自大肠杆菌O111:B4的脂多糖(LPS)已用于巨噬细胞的刺激。它们在小鼠中已用于LPS的预处理。
脂多糖(LPS)是革兰氏阴性菌细胞壁的特征组分。LPS及其脂质A部分可通过能够识别常见的病原体相关分子模式(PAMP)的Toll样受体蛋白家族成员Toll样受体4(TLR4)刺激先天性免疫系统细胞。
包装:10mg，25mg，100mg in poly bottle
制备说明:
该产物可溶于水(5mg/ml)或细胞培养基(1mg/ml)，产生模糊的淡黄色溶液。以中更为浓缩但仍然模糊的溶液(20mg/ml)可形成于涡旋并升温至70-80°C后。脂多糖是在每种溶剂中都形成胶束的分子。在水和磷酸盐缓冲液中都能观察到模糊的溶液。有机溶剂也不会产生更为清澈的溶液。甲醇可产生具有漂浮物的混浊悬浮液，而水则能产生均匀模糊的溶液。
一、╳※试剂※╳:
常规血清优势供应:VivaCell货号C04001-500血清、Gemini货号900-108血清、Gemini血清、Gibco血清(10099-141澳洲血清、10270-106南美血清、16000-044血清)、BI血清BI货号04-001-1ACS、Sigma货号F8318-500ml澳洲胎牛血清、Sigma货号F8687澳洲胎牛血清、Sigma货号F2442-500ml特级胎牛血清、ScienCell货号0500澳洲胎牛血清、Cegrogen货号A0500-3010胎牛血清、Cegrogen货号B0500-5010新生牛血清、康源血清
培养基(包括无血清)、冻存液(包括无血清)，包括:友康Yocon
Merck(Millipore/Sigma/Roche/KaPa/Supelco/Avanti/Corning/Brand)正式授权代理、博奥龙Biodragon独家总代理、EFL独家总代理、碧云天Beyotime代理
☆☆☆☆☆☆Beckman货号A63881纯化磁珠Agencourt AMPure XP(60ml/瓶)/A63882(450ml/瓶)；Beckman货号B23317核酸片段筛选试剂盒Agencourt SPRIselect(5ml/瓶)
分子类:Biotium货号41003的GelRed染料、货号31000的EvaGreen染料、Zymo Research、Qiagen
饲料类:Research Diets、Dyets
二、╳※耗材※╳:
洁特JET耗材(各类常规用实验耗材)、赛普Cellpro耗材/KirGen耗材、博麦迪(常规的)各类试剂瓶
Bioplastics
Thermo Fisher Scientific的很多产品线，包括旗下的:
一、Nunc耗材
二、QSP耗材(各类吸头/滤芯吸头、离心管、PCR管等)
三、Nalgene耗材仪器
四、FisherBrand耗材仪器(含各类盖玻片载玻片等)
五、Lab_Serv耗材仪器
六、Finnpipette移液器(如：F1系列、F2系列、F3系列等等各类型号的移液器)
七、Abgene耗材
畅销款:我们是常备有大量现货的
可请随时咨询:万奎13611631389(可以请加微信)
※╳√√✓✔√✓✔√✓✔上海睿安生物科技有限公司成立于2009年，专注于为生命科学和生物技术领域的客户提供优质的产品与服务。代理了多家欧美知名品牌，如美国Thermo Fisher耗材(包括旗下Nunc、QSP、Nalgene、FisherBrand、Lab_Serv耗材仪器、Finnpipette移液器、Abgene耗材，等等)、默克Merck-Millipore/Sigma/Roche/KaPa/Supelco/Avanti/Corning/Brand)、Zymo Research、洁特JET耗材(各类常规用实验耗材)、赛普Cellpro耗材、博奥龙Biodragon独家总代理、EFL独家总代理、碧云天Beyotime代理、Eppendorf、友康Yocon、Research Diets高脂饲料，IBL、BioVendor、Mercodia、ShiBayaji代谢类产品、Axygen-Corning长期大量耗材备货、BioCaot畅销款长期备货，VivaCell血清、Gemini血清、Gibco血清，BI血清现货、ScienCell血清、Sigma血清、Moregate血清、Cegrogen血清、Pierce发光试剂、Fermentas、Invitrogen、Abcam、CST、BD、SAB、R&D systems、Beckman、Qiagen、BD Pharmingen、Biolegend、Jackson、Miltenyi、MP Biomedicals、Biotium更好的荧光试剂产品等品牌。睿安生物始终将“提供更好的产品和服务”作为企业发展的目标和努力的方向，并将通过优质的售前与售后服务，始终如一地为客户提供高质量的产品和服务，我们也希望能得到相关领域中更多老师和同仁们的指导和鞭策，为共创优秀品牌而努力奋斗！询订╳直线13611631389微信号
Jianbo Yu et al.
Anesthesiology, 125(6), 1190-1201 (2016-08-31)
Sepsis-associated acute lung injury remains the major cause of mortality in critically ill patients and is characterized by marked oxidative stress and mitochondrial dysfunction. Mitochondrial dynamics are indispensable for functional integrity. Additionally, heme oxygenase (HO)-1/carbon monoxide conferred cytoprotection against end-organ
Conserved gene regulation during acute inflammation between zebrafish and mammals.
G Forn-Cuní et al.
Scientific reports, 7, 41905-41905 (2017-02-06)
Zebrafish (Danio rerio), largely used as a model for studying developmental processes, has also emerged as a valuable system for modelling human inflammatory diseases. However, in a context where even mice have been questioned as a valid model for these
Outer membrane permeability and antibiotic resistance.
Delcour AH et al.
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 1794, 808-816 (2009)
Corticotropin-releasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice.
Agelaki S et al.
Infection and Immunity, 70, 6068-6068 (2002)
Systematic Identification and Analysis of Expression Profiles of mRNAs and Incrnas in Macrophage Inflammatory Response.
Lei Li et al.
Shock (Augusta, Ga.), 51(6), 770-779 (2018-12-19)
Long noncoding RNAs (lncRNAs), once thought to be transcriptional noise, have been recently shown to regulate a variety of biological processes. However, their roles in the inflammatory response are largely unexplored. In this study, we performed high-throughput sequencing to identify
同行评审论文
Heme Oxygenase-1/Carbon Monoxide-regulated Mitochondrial Dynamic Equilibrium Contributes to the Attenuation of Endotoxin-induced Acute Lung Injury in Rats and in Lipopolysaccharide-activated Macrophages.Jianbo Yu et al.
Anesthesiology, 125(6), 1190-1201 (2016-08-31)
Sepsis-associated acute lung injury remains the major cause of mortality in critically ill patients and is characterized by marked oxidative stress and mitochondrial dysfunction. Mitochondrial dynamics are indispensable for functional integrity. Additionally, heme oxygenase (HO)-1/carbon monoxide conferred cytoprotection against end-organ
Conserved gene regulation during acute inflammation between zebrafish and mammals.
G Forn-Cuní et al.
Scientific reports, 7, 41905-41905 (2017-02-06)
Zebrafish (Danio rerio), largely used as a model for studying developmental processes, has also emerged as a valuable system for modelling human inflammatory diseases. However, in a context where even mice have been questioned as a valid model for these
Outer membrane permeability and antibiotic resistance.
Delcour AH et al.
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 1794, 808-816 (2009)
Corticotropin-releasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice.
Agelaki S et al.
Infection and Immunity, 70, 6068-6068 (2002)
Systematic Identification and Analysis of Expression Profiles of mRNAs and Incrnas in Macrophage Inflammatory Response.
Lei Li et al.
Shock (Augusta, Ga.), 51(6), 770-779 (2018-12-19)
Long noncoding RNAs (lncRNAs), once thought to be transcriptional noise, have been recently shown to regulate a variety of biological processes. However, their roles in the inflammatory response are largely unexplored. In this study, we performed high-throughput sequencing to identify
技术资料需要更多技术资料 索取更多技术资料
资料下载：
默克化工&睿安2022授权书.pdf 附 (下载 0 次)
默克化工&睿安2022授权书.png 附 (下载 0 次)
Sigma货号L2630-10mg脂多糖LPS.jpg 附 (下载 7 次)
Sigma货号L2630-100mg脂多糖LPS询订13611631389.jpg 附 (下载 5 次)
Sigma-2.jpg 附 (下载 1 次)
⁺询订13611631389微信同号.png 附 (下载 0 次)
Merck.jpg 附 (下载 1 次)
请 [登录] 后再下载!
文献支持
Sigma L2630-100mg脂多糖LPS刺激细胞13611631389上海睿安生物
￥4655.74
