Recombinant Influenza A H1N1 (A/Taiwan/01/1986) HA Protein
Catalog #: DRA127 Derived From: Human Cells
Description:
Recombinant Influenza A H1N1 (A/Taiwan/01/1986) HA Protein is produced by our Mammalian expression system and the target gene encoding Asp18-Gln529 is expressed with a 6His tag at the C-terminus.
Accession: Q1K9L3
Names(Known as): Hemagglutinin; HA; A H1N1 (A/Taiwan/01/1986) HA Protein
Quality Control:
Mol Mass: 62.2kDa AP Mol Mass: 80-100kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Shipping:
The product is shipped on dry ice pack.
Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Application:
Immunogen, calibrator or standard.
Background:
HA is class I viral fusion protein, binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY