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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C/-80°C
- 保质期:
12个月
- 英文名:
Recombinant Human Growth/differentiation factor 5(GDF5)
- 库存:
4
- 供应商:
上海禾午生物科技有限公司
- 规格:
20ug/100ug/1mg
产品详情
纯度:> 95 % as determined by SDS-PAGE and HPLC analyses.
内毒素:Less than 0.1 EU/ug as determined by LAL method.
生物活性:Fully biologically active when compared to standard. The ED50 as determined by inducing alkaline phosphatase production of murine ATDC5 cells is less than 1.0 μg/ml, corresponding to a specific activity of > 1000 IU/mg.
基因名:GDF5
Uniprot No.:P43026
别名:BMP14; Cartilage derived morphogenetic protein 1; Cartilage-derived morphogenetic protein 1; CDMP-1; CDMP1; GDF-5; Gdf5; GDF5_HUMAN; Growth differentiation factor 5; Growth/differentiation factor 5; LAP4; OS5; Radotermin; SYNS2
种属:Homo sapiens (Human)
蛋白长度:Full Length of Mature Protein
来源:E.Coli
分子量:13.6 kDa
表达区域:382-501aa
蛋白标签:Tag-Free
产品提供形式:Liquid or Lyophilized powder
功能:参与骨骼和软骨形成的生长因子。在软骨发育过程中,通过两条途径调控软骨组织的分化。首先,通过与BMPR1B高亲和性结合,与BMPR1A低亲和性结合,正向调控软骨组织的分化,诱导SMAD1-SMAD5-SMAD8复合体磷酸化,进而诱导SMAD蛋白信号转导。其次,通过与NOG的交互作用负向调节软骨分化。需要防止过度的肌肉丧失去神经。该功能需要SMAD4,并由磷酸化的SMAD1/5/8介导。结合细菌脂多糖(LPS),介导LPS诱导的炎症反应,包括单核细胞分泌TNF。
更多活性蛋白请浏览上海禾午生物科技有限公司
上海禾午生物科技有限公司 提供重组蛋白生产服务 His、GST、MBP等多种表达方式同时进行,确保获得蛋白
蛋白表达与纯化服务 纯化的蛋白经过ELISA,Western-blot,或者其它生物活性验证 标签切除 测序报告
上海禾午生物科技有限公司是一家生物高新技术企业,产品覆盖分子生物学、细胞生物学、生物学试剂、标准物质,等领域。以研发、销售为核心致力于生命科学产品。已与全国各大科研院校、医院、企业以及国外一些科研机构有良好的合作关系。
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文献和实验【分享】Human press METHODS IN MOLECULAR BIOLOGY
, Christine, 2000 141.Plant Hormone Protocols Edited by Tucker, Gregory A..2000 142.Transforming Growth Factor-Beta Protocols. Edited by Howe, Philip H., 2000 143.Protein Structure Prediction: Methods and Protocols Edited by Webster, David , 2000 144
Introduction of human 14-3-3 proteins
of Pseudomonas aeruginosa as does bovine brain factor activating exoenzyme S (FAS),which is itself a member of 14-3-3 proteins.In addition,GF14 omega binds calcium,as does the human 14-3-3 homologue reported to be a phospholipase A2.These results indicate
Culturing BG01V Human Embryonic Stem Cells with Mouse Embryonic Fibroblast (MEF)-Conditioned Media
(approximately 1.0 x 106 cells/60 mm plate) on the Cultrex BME coated plate in Conditioned Media containing 4 ng/mL of recombinant human FGF basic. Change the media daily. Monitor the cells for the desired confluency. Figure
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