D-Isofloridoside,23202-76-8

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D-Isofloridoside

CAS No. : 23202-76-8

MCE 国际站：D-Isofloridoside

产品活性：D-Isofloridoside 是多糖前体之一，具有清除自由基、抑制 ROS 表达、抑制 MMP-2 和 MMP-9 的活性。

研究领域：Immunology/Inflammation  |  NF-κB  |  Metabolic Enzyme/Protease

作用靶点：Reactive Oxygen Species  |  MMP

In Vitro: D-Isofloridoside can reduce the activity of MMP-2/9, and can inhibit the expression of hypoxia-inducible factor-1α (HIF-1α) by regulating the downstream PI3K/AKT and MAPK pathways, thereby down-regulating the production of vascular endothelial growth factor (VEGF) in CoCl₂-induced HT1080 cell. D-Isofloridoside can inhibit the activation of VEGF receptor (VEGFR-2), regulate downstream PI3K/AKT, MAPK, NF-κB signal pathways, activate apoptosis, and thus down-regulate the production of platelet-derived growth factor (PDGF) in VEGF-induced HUVEC.

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