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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
683239-16-9
- 规格：
1 g/5 g/10 g/25 g
| 规格： | 1 g | 产品价格： | ￥125.0 |
|---|---|---|---|
| 规格： | 5 g | 产品价格： | ￥395.0 |
| 规格： | 10 g | 产品价格： | ￥778.0 |
| 规格： | 25 g | 产品价格： | ￥1626.0 |
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20-(tert-Butoxy)-20-oxoicosanoic acid
CAS No. : 683239-16-9
MCE 国际站：20-(tert-Butoxy)-20-oxoicosanoic acid
产品活性：20-(tert-Butoxy)-20-oxoicosanoic acid 是不可降解 (non-cleavable) 的 ADC linker，用于合成抗体偶联活性分子 (ADCs)。20-(tert-Butoxy)-20-oxoicosanoic acid 也是一个基于烷基链 (alkyl chain) 的 PROTAC linker，可用于合成 PROTAC。
研究领域：Antibody-drug Conjugate/ADC Related | PROTAC
作用靶点：ADC Linker | PROTAC Linkers
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
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文献和实验The determination of sulfur amino acids, glutathione (GSH), and related aminothiols has been carried out by isotachophoresis (1 ), amino acid analyzer (AAA) (2 ,3 ), gas chromatography (GC) (4 –8 ), high-performance liquid chromatography
Uracil‐1‐yl acetic acid (2 ; protocol 1 ) N ‐(2‐((tert ‐Butyldimethylsilyl)oxy)ethyl)prop‐2‐yn‐1‐amine (8 ; protocol
, and the reaction is carried out at 70°C. Subsequently, workup, isolation, and purification lead to the requisite O 6 ?alkyl or O 6 ?aryl ethers in good to excellent yields. Curr. Protoc. Nucleic Acid Chem. 49:1.26.1?1.26.16. © 2012 by John Wiley & Sons
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