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Active Motif公司是一家致力于研发和生产核细胞分子生物学和表观遗传学研究用试剂的专业公司,也是世界著名的转录因子试剂生产商和CHIP-seq外包服务供应商。
Active Motif的产品涉及:表观遗传学相关抗体、Chip级别抗体、重组识别子和催化酶、预甲基化修饰的重组组蛋白、多聚核小体和生物素标记核小体;以及各类染色质分析、转录因子表达调控分析和DNA甲基化分析的试剂盒等。
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文献和实验Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library
A. Select a cell line that either does not express or expresses low levels of your miRNA of interest. The miRNA will be introduced in Section B for target selection after stable expression of the Target ID Library is achieved.
Validating microRNA Target Transcripts Using Zebrafish Assays
are regulators of gene expression that bind target mRNAs and modulate their translation and turnover. The specificity of this regulation is achieved by partial sequence complementarity between the miRNA and its target mRNA. Understanding which mRNAs are targeted
Experimental Validation of MicroRNA Targets Using a Luciferase Reporter System
. Currently, the only available tools to validate a sequence as a direct target of an miRNA are the systems based on a reporter gene carrying the candidate sequence. Here, an miRNA target validation reporter gene system based on the luminescence generated by the luciferase
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