Anti-Active CASP3 Monoclonal A

Anti-Active CASP3 Monoclonal Antibody

产品简介

英文名称	Anti-Active CASP3 Monoclonal Antibody
别名	CASP-3;CPP-32;SCA-1
宿主	Mouse
稀释比例	WB 1:1000-3000. IHC 1:100-300.
Gene ID	836
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P42574
蛋白分子量	32kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm
免疫原	Recombinant Protein
亚型	IgG1
纯化方法	Affinity purification
克隆号	5.00E+01
背景资料	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
克隆类型	Monoclonal Antibody
交叉反应	Human Rat Mouse
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Immunohistochemistry of paraffin-embedded Human testis cancer with Active CASP3 antibody diluted at 1:200

Immunohistochemistry of paraffin-embedded Human stomach cancer with Active CASP3 antibody diluted at 1:200

Western blot analysis with Active CASP3 antibody diluted at 1:2000;Lane:Rat brain