Anti-IFT57 Polyclonal Antibody

Anti-IFT57 Polyclonal Antibody



产品简介

英文名称	Anti-IFT57 Polyclonal Antibody
靶标	GPRC5B
别名	CDNA FLJ10147 fis clone HEMBA1003369; Dermal papilla derived protein 8; Dermal papilla-derived protein 8; DERP 8; DERP8; Esrrbl 1; Esrrbl1; ESRRBL1 protein; Estrogen related receptor beta like 1; Estrogen related receptor beta like protein 1; Estrogen-related receptor beta-like protein 1; FLJ10147; Hip1 Interacting protein; HIP1 interacting protein HIPPI; Hip1 protein interactor; HIP1-interacting protein; HIPPI; Huntingtin interacting protein 1 interacting protein; Huntingtin interacting protein 1 protein interactor; IFT 57; ift57; IFT57_HUMAN; Intraflagellar transport 57 homolog (Chlamydomonas); Intraflagellar transport 57 homolog; Intraflagellar transport protein 57 homolog; MHS4R2; Vestrogen related receptor beta like 1;
宿主	Rabbit
稀释比例	WB 1:1000-3000. IHC 1:50-200.
Gene ID	55081
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q9NWB7
蛋白分子量	49kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm
免疫原	A synthetic peptide of human IFT57
亚型	IgG
纯化方法	Affinity purification
背景资料	Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Public Immunogen Range	140-190/429aa
克隆类型	Polyclonal Antibody
交叉反应	Human Predicted:Cow Rat Mouse
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with IFT57 antibody diluted at 1:2000;Lane:U251MG

Immunohistochemistry of paraffin-embedded Human colorectal cancer using IFT57 antibody diluted at 1:100