Anti-HEXB Polyclonal Antibody

Anti-HEXB Polyclonal Antibody


产品简介

英文名称	Anti-HEXB Polyclonal Antibody
别名	ENC-1AS;HEL-248;HEL-S-111;HEXB;HCC 7;HCC-7
宿主	Rabbit
稀释比例	WB 1:1000-3000.
Gene ID	3074
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P07686
蛋白分子量	63kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm
免疫原	A synthetic peptide of human HEXB
亚型	IgG
纯化方法	Octanoic acid-ammonium sulfate precipitation
背景资料	Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Public Immunogen Range	80-130/556aa
克隆类型	Polyclonal Antibody
交叉反应	Human
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with HEXB antibody diluted at 1:2000;Lane:HepG2,Jurka