- ￥960
- Solarbio
- 中国 北京
- K110681P-50ul
- 2025年07月12日
- IHC
- Rabbit
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- 详细信息
- 技术资料
- 免疫原：
A synthetic peptide of human APH1A
- 亚型：
IgG
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 靶点：
APH1A
- 规格：
50ul
Anti-APH1A Polyclonal Antibody
产品简介
| 靶标 | APH1A |
| 别名 | APH1A;6530402N02Rik;APH-1;APH-1A;CGI-78 |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 51107 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q96BI3 |
| 蛋白分子量 | 21/27/29kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human APH1A |
| 亚型 | IgG |
| 纯化方法 | Octanoic acid-ammonium sulfate precipitation |
| 背景资料 | This gene encodes a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein. The gamma secretase complex contains this gene product, or the paralogous anterior pharynx defective 1 homolog B (APH1B), along with the presenilin, nicastrin, and presenilin enhancer-2 proteins. The precise function of this seven-transmembrane-domain protein is unknown though it is suspected of facilitating the association of nicastrin and presenilin in the gamma secretase complex as well as interacting with substrates of the gamma secretase complex prior to their proteolytic processing. Polymorphisms in a promoter region of this gene have been associated with an increased risk for developing sporadic Alzheimer's disease. Alternative splicing results in multiple protein-coding and non-protein-coding transcript variants. |
| Public Immunogen Range | 215-265/265 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human Mouse |
| 应用 | IHC |
| 规格 | 50ul 100ul |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Immunohistochemistry of paraffin-embedded Human endometrial cancer using APH1A antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human renal cancer using APH1A antibody diluted at 1:100.
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Anti-APH1A Polyclonal Antibody
￥960
