Anti-KPNA6 Polyclonal Antibody

Anti-KPNA6 Polyclonal Antibody


产品简介

英文名称	Anti-KPNA6 Polyclonal Antibody
别名	Importin subunit alpha-7;Karyopherin subunit alpha-6;IPOA7;
宿主	Rabbit
稀释比例	IHC 1:100-300.
Gene ID	23633
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	O60684
蛋白分子量	60kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Nucleus Cytoplasm
免疫原	Recombinant protein of human KPNA6
亚型	IgG
纯化方法	Affinity purification
背景资料	Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.
Public Immunogen Range	188-537aa
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Immunohistochemistry of paraffin-embedded Human Human breast cancer with KPNA6 antibody diluted at 1:200