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文献和实验Generation of Short-Term Murine Natural Killer Cell Clones to Analyze Ly49 Gene Expression
Natural killer (NK) cellsexpress receptors specific for class I major histocompatibility complex (MHC) molecules. In the mouse, the class I specific receptors identified to date belong to the polymorphic Ly49 receptor family. Engagement of Ly49
the Swiss Webster or CD1 outbred strains, although past usage includes both C57Bl/6 and B6C3F1. The Anesthetic Avertin (2,2,2 tribromoethanol) is found to be quite effective. For method of preparation, see "Manipulating the Mouse Embryo", CSHL
Hybrid Resistance by Mouse NK Cells In Vitro
of monoclonal antibodies (MAbs) or F(ab′)2 reagents to block those signals. There is already good evidence for negative signals between Ly49 NK cell receptors and their specific class I antigens, e.g., Ly49A and H2-Dd (2 ). Thus, the inability of H2b Ly49
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