Mouse IFN-γ 重组小鼠γ干扰素(小鼠γ干扰素)

Mouse IFN-γ 重组小鼠γ干扰素(小鼠γ干扰素)

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  • ¥1668
  • 翌圣生物(Yeasen)已认证
  • 91212ES60
  • 上海
  • 2025年10月16日
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    • 详细信息
    • 技术资料
    • 保质期

      有效期1年

    • 保存条件

      -20℃至-80℃保存

    • 供应商

      翌圣生物科技(上海)股份有限公司

    • 库存

      大量

    • 英文名

      Recombinant Mouse Interferon-gamma (Mouse IFN-γ)

    • 规格

      100μg

    Product Information

     

    Product Name

    Cat#

    Size

    Price(¥

    Recombinant Mouse Interferon-gamma (Mouse IFN-γ)

    91212ES60

    100 μg

    1855.00

    91212ES76

    500 μg

    7495.00

     

    Product Description

     

    Interferon-gamma (IFN-γ), also known as Type II interferon or immune interferon, is a pleiotropic cytokine which is now recognised as an important modulator of the immune response. Mature human IFN-γ exists as a non-covalently linked homodimer of 20-25 kDa variably glycosylated subunits. It shares 90% amino acid (aa) sequence identity with rhesus IFN-γ, 59%64% with bovine, canine, equine, feline, and porcine IFN-γ, and 37%43% with cotton rat, mouse, and rat IFN-γ. Interferons have had increasing clinical usage in the treatment of a variety of disorders, at times being used in combination with chemo‐ or radiotherapy.IFN-γ increases the potential immunogenicity of vascular endothelial cells by up-regulation of intercellular adhesion molecule-1 (ICAM-1) and class I MHC antigen expression and by induction of class II MHC antigens and certain chemokines.

     

    Product Properties

     Mouse IFN-γ 重组小鼠γ干扰素(小鼠γ干扰素)

    Synonyms

    Interferon-gamma, IFN-γ, IFG, IFI, IFNG, IFNgamma, IFN-gamma.

    Accession

    P01580

    GeneID

    15978

    Source

    E.coli-derived mouse IFN-γ protein, His23-Cys155.

    Molecular Weight

    Approximately 15.5 kDa.

    AA Sequence

    HGTVIESLES LNNYFNSSGI DVEEKSLFLD IWRNWQKDGD MKILQSQIIS FYLRLFEVLK DNQAISNNIS VIESHLITTF FSNSKAKKDA FMSIAKFEVN NPQVQRQAFN ELIRVVHQLL PESSLRKRKR SRC

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    > 96 % by SDS-PAGE and HPLC analyses.

    Biological Activity

    The ED50 as determined by an anti-viral assay using murine L929 cells infected with encephalomyocarditis (EMC) virus is less than 0.8 ng/ml, corresponding to a specific activity of > 1.3 × 106 IU/mg. Fully biologically active when compared to standard.

    Endotoxin

    < 1.0 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, containing 5 % trehalose.

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

     

    The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions

     

    Avoid repeated freeze-thaw cycles.

    For your safety and health, please wear lab coats and disposable gloves for operation.

    For research use only.

     

    HB220210

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