KYSE520/KYSE520/KYSE520/人食管鳞癌细

KYSE520/KYSE520细胞系/KYSE520细胞株/KYSE520人食管鳞癌细胞

Cell line name KYSE-520

Synonyms KYSE 520; KYSE520; Kyse520; KYSE0520

Accession CVCL_1355

Resource Identification Initiative To cite this cell line use: KYSE-520 (RRID:CVCL_1355)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Population: Japanese.

Doubling time: 30.2 hours (PubMed=1728357); ~30 hours (DSMZ=ACC-371).

Microsatellite instability: Stable (MSS) (Sanger).

Omics: CRISPR phenotypic screen.

Omics: Deep exome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.

PubMed=11092977; DOI=10.1111/j.1349-7006.2000.tb00895.x; PMCID=PMC5926289

Pimkhaokham A., Shimada Y., Fukuda Y., Kurihara N., Imoto I., Yang Z.-Q., Imamura M., Nakamura Y., Amagasa T., Inazawa J.

Nonrandom chromosomal imbalances in esophageal squamous cell carcinoma cell lines: possible involvement of the ATF3 and CENPF genes in the 1q32 amplicon.

Jpn. J. Cancer Res. 91:1126-1133(2000)

 

PubMed=11520067; DOI=10.1006/bbrc.2001.5400

Kan T., Shimada Y., Sato F., Maeda M., Kawabe A., Kaganoi J.-i., Itami A., Yamasaki S., Imamura M.

Gene expression profiling in human esophageal cancers using cDNA microarray.

Biochem. Biophys. Res. Commun. 286:792-801(2001)

 

PubMed=12963126; DOI=10.1016/S0304-3835(03)00344-6

Hoque M.O., Begum S., Sommer M., Lee T., Trink B., Ratovitski E., Sidransky D.

PUMA in head and neck cancer.

Cancer Lett. 199:75-81(2003)

 

PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172

Sonoda I., Imoto I., Inoue J., Shibata T., Shimada Y., Chin K., Imamura M., Amagasa T., Gray J.W., Hirohashi S., Inazawa J.

Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.

Cancer Res. 64:3741-3747(2004)

 

PubMed=16045545; DOI=10.1111/j.0959-9673.2005.00431.x; PMCID=PMC2517430

Ban S., Michikawa Y., Ishikawa K.-i., Sagara M., Watanabe K., Shimada Y., Inazawa J., Imai T.

Radiation sensitivities of 31 human oesophageal squamous cell carcinoma cell lines.

Int. J. Exp. Pathol. 86:231-240(2005)

 

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113

Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

Signatures of mutation and selection in the cancer genome.

Nature 463:893-898(2010)

 

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662

Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Cancer Res. 70:2158-2164(2010)