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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
KYSE180
- 库存:
1x10^6/瓶/支
- 供应商:
上海酶研
- 肿瘤类型:
详询
- 细胞类型:
人食道癌肿瘤细胞
- ATCC Number:
详询
- 品系:
KYSE180
- 组织来源:
人食道癌肿瘤细胞
- 相关疾病:
KYSE180
- 物种来源:
哺乳动物
- 免疫类型:
详询
- 细胞形态:
贴壁/悬浮
- 是否是肿瘤细胞:
详询
- 器官来源:
人食道癌肿瘤细胞
- 运输方式:
顺丰快递
- 年限:
5年
- 生长状态:
生长良好
KYSE180/KYSE180细胞系/KYSE180细胞株/KYSE180人食道癌肿瘤细胞
Cell line name KYSE-180
Synonyms KYSE 180; KYSE180; Kyse180; KY180
Accession CVCL_1349
Resource Identification Initiative To cite this cell line use: KYSE-180 (RRID:CVCL_1349)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Doubling time: 15.2 hours (PubMed=1728357); ~40-50 hours (DSMZ=ACC-379).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
PubMed=7913084; DOI=10.1002/ijc.2910580224
Kanda Y., Nishiyama Y., Shimada Y., Imamura M., Nomura H., Hiai H., Fukumoto M.
Analysis of gene amplification and overexpression in human esophageal-carcinoma cell lines.
Int. J. Cancer 58:291-297(1994)
PubMed=8575860; DOI=10.1002/(SICI)1097-0215(19960126)65:3<372::AID-IJC16>3.0.CO;2-C
Tanaka H., Shibagaki I., Shimada Y., Wagata T., Imamura M., Ishizaki K.
Characterization of p53 gene mutations in esophageal squamous cell carcinoma cell lines: increased frequency and different spectrum of mutations from primary tumors.
Int. J. Cancer 65:372-376(1996)
PubMed=9033652; DOI=10.1002/(SICI)1097-0215(19970207)70:4<437::AID-IJC11>3.0.CO;2-C
Tanaka H., Shimada Y., Imamura M., Shibagaki I., Ishizaki K.
Multiple types of aberrations in the p16 (INK4a) and the p15(INK4b) genes in 30 esophageal squamous-cell-carcinoma cell lines.
Int. J. Cancer 70:437-442(1997)
PubMed=11092977; DOI=10.1111/j.1349-7006.2000.tb00895.x; PMCID=PMC5926289
Pimkhaokham A., Shimada Y., Fukuda Y., Kurihara N., Imoto I., Yang Z.-Q., Imamura M., Nakamura Y., Amagasa T., Inazawa J.
Nonrandom chromosomal imbalances in esophageal squamous cell carcinoma cell lines: possible involvement of the ATF3 and CENPF genes in the 1q32 amplicon.
Jpn. J. Cancer Res. 91:1126-1133(2000)
PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172
Sonoda I., Imoto I., Inoue J., Shibata T., Shimada Y., Chin K., Imamura M., Amagasa T., Gray J.W., Hirohashi S., Inazawa J.
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Cancer Res. 64:3741-3747(2004)
PubMed=16045545; DOI=10.1111/j.0959-9673.2005.00431.x; PMCID=PMC2517430
Ban S., Michikawa Y., Ishikawa K.-i., Sagara M., Watanabe K., Shimada Y., Inazawa J., Imai T.
Radiation sensitivities of 31 human oesophageal squamous cell carcinoma cell lines.
Int. J. Exp. Pathol. 86:231-240(2005)
PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)
PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)
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文献和实验*发表【中文论文】请标注:由上海酶研生物科技有限公司提供;
*发表【英文论文】请标注:From Shanghai EK-Bioscience Biotechnology Co., Ltd.
Constructing a Low-budget Laser Axotomy System to Study Axon Regeneration in C. elegans
40 1 Rail carrier for X26, square 40mm length Newport CN26-40 4
年2月《科学》上的一篇报告指出,美国过敏与免疫学研究所的研究人员发现,当肿瘤抑制蛋白p53不仅存在于细胞核内时能抑制肿瘤细胞,存在于细胞核外的液体中时还能诱导癌细胞凋亡。当p53存在于肿瘤细胞的细胞质中时,能激活Bax--一种促进细胞死亡的Bcl-2同类蛋白。被p53激活的Bax能破坏细胞线粒体引起细胞死亡。大多数肿瘤细胞中都存在p53蛋白,p53被视作基因组卫士。科学家早就知道p53是在细胞核内通过调控关键细胞过程如细胞周期调控、细胞死亡和DNA修复等发挥抑制肿瘤作用,但这次是首次发现p53在细胞
盘点 2020 年中国学者的十大免疫学研究成果,有的已经被写进高考题?!
的。2020 年 6 月 11 日,中山大学中山医学院宋尔卫院士、苏士成教授团队在 Nature 上在线发表了题为 DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25 的研究成果 (6)。该研究发现 肿瘤细胞膜上的蛋白 CCDC25 可作为 NET-DNA 受体感知胞外 DNA,进而介导肿瘤转移的发生;监测血液样本中的 NET-DNA 可能作为评估肿瘤患者预后的一种方法。 图片来源:Nature先前的研究
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