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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
None
- 亚型:
IgG2b, kappa
- 保存条件:
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
FITC Plus Fluorescent Dye
- 适应物种:
mouse
- 保质期:
详见产品包装
- 库存:
充足
- 宿主:
Rat
- 应用范围:
FC
- 靶点:
Ly-6G/Ly-6C (Gr-1)
- 抗体英文名:
FITC Plus Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5)
- 抗体名:
FITC Plus Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5)
- 规格:
25ug/100ug
| 规格: | 25ug | 产品价格: | ¥600.0 |
|---|---|---|---|
| 规格: | 100ug | 产品价格: | ¥1200.0 |
经过测试的应用
| Positive FC detected in | mouse bone marrow cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
FITC-65140 targets Ly-6G/Ly-6C (Gr-1) in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 文献引用应用 | FC |
| 经测试反应性 | mouse |
| 文献引用反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG2b, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | lymphocyte antigen 6 complex, locus G |
| 别名 | Ly6g, RB6-8C5, Ly-6G, Ly 6G |
| GenBank蛋白编号 | X70920 |
| 基因名称 | Ly-6G |
| Gene ID (NCBI) | 546644 |
| RRID | AB_2883800 |
| 偶联类型 | FITC Plus Fluorescent Dye |
| 最大激发/发射波长 | 495 nm / 524 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P35461 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Ly-6G (lymphocyte antigen 6 complex, locus G), also known as Gr-1, is a 21-25 kDa, glycosylphosphatidylinositol-anchored protein expressed on myeloid lineage cells in mouse bone marrow (PMID: 8360469). The expression of Ly-6G increases on neutrophils as they differentiate from immature cells in the bone marrow to mature cells in the blood and spleen (PMID: 8890901). Antibodies targeting Ly6G (RB6-8C5 or 1A8) are commonly used in studies aimed at identifying the role of neutrophils (PMID: 23543767). The RB6-8C5 mAb has been reported to cross-react with Ly-6C on cells expressing Ly-6C (PMID: 8360469).
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse | FC | Adv Sci (Weinh) Cancer-Associated Fibroblast-Induced Remodeling of Tumor Microenvironment in Recurrent Bladder CancerAuthors - Ting Liang |
| mouse | FC | Front Immunol Endogenous α7 nAChR Agonist SLURP1 Facilitates Escherichia coli K1 Crossing the Blood-Brain Barrier.Authors - Xiaolong He |
| mouse | FC | J Nanobiotechnology The combination of modified acupuncture needle and melittin hydrogel as a novel therapeutic approach for rheumatoid arthritis treatmentAuthors - Lisha Liu |
11b)-IgG2b-FITC 1:100 Pharmingen 553310 Gr-1(Ly6G)-IgG2b-FITC 1:100 Pharmingen 553127 CD3-IgG2b-FITC 1:100 Pharmingen 555274
D Granulocytic : Gr-1 (Ly-6G) IgG2b, 01211A D8 IgG2b, 09821D Eryth: Ter-119 IgG2b, 09081A Sca-1 PE-IgG2a (E31-161.7) 01835B PE-IgG2a Isotype control, 11025
Isolation Kit CD5(Ly-1) MicroBeadsCD8a(Ly-2) MicroBeadsCD8a+ T Cell Isolation Kit CD25 MicroBead KitCD62L(L-selectin) MicroBeadsAnti-MHC class II MicroBeadsCD4-FITC/PE/APCCD8a-FITC/PE/APCCD25-PECD62L-FITC/PE/APCCD90-FITC/PE/APC细胞因子分泌细胞Mouse IFN-r Secretion
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