- ￥600 - 1200
- Proteintech
- FITC-65069
- 2025年10月13日
- FC
- Rat
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG2a, kappa
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
FITC Plus Fluorescent Dye
- 适应物种：
Mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rat
- 应用范围：
FC
- 靶点：
CD8a
- 抗体英文名：
FITC Plus Anti-Mouse CD8a (53-6.7)
- 抗体名：
FITC Plus Anti-Mouse CD8a (53-6.7)
- 规格：
25ug/100ug
| 规格： | 25ug | 产品价格： | ￥600.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥1200.0 |
经过测试的应用
| Positive FC detected in | mouse splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
FITC-65069 targets CD8a in FC applications and shows reactivity with Mouse samples.
| 经测试应用 | FC |
| 文献引用应用 | FC |
| 经测试反应性 | Mouse |
| 文献引用反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG2a, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | CD8 antigen, alpha chain |
| 别名 | BB154331, CD8 antigen, alpha chain, CD8a, CD8α, Ly 2, Ly 35, Ly B, Lyt 2 |
| GenBank蛋白编号 | BC030679 |
| 基因名称 | Cd8a |
| Gene ID (NCBI) | 12525 |
| RRID | AB_2883759 |
| 偶联类型 | FITC Plus Fluorescent Dye |
| 最大激发/发射波长 | 495 nm / 524 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P01731 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells, on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084).
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse | FC | ACS Appl Mater Interfaces Intelligent Nanoplatform Integrating Macrophage and Cancer Cell Membrane for Synergistic Chemodynamic/Immunotherapy/Photothermal Therapy of Breast CancerAuthors - Shichao Zhang |
| FC | Oncogene ZG16 enhances the maturation of dendritic cells via induction of CD40 and contributes to the antitumor immunity in pancreatic cancerAuthors - Hui Meng | |
| FC | J Pharm Biomed Anal Altered gut metabolites and metabolic reprogramming involved in the pathogenesis of colitis-associated colorectal cancer and the transition of colon "inflammation to cancer"Authors - Dunfang Wang | |
| mouse | FC | Biol Direct HOXB4/METTL7B cascade mediates malignant phenotypes of hepatocellular carcinoma through TKT m6A modificationAuthors - Enshuang Guo |
Theranostics Optimized circular RNA vaccines for superior cancer immunotherapyAuthors - Hongwu Yu | ||
| FC | J Mol Neurosci Proteomic Profiling and Therapeutic Targeting of Oxidative Stress in Autoimmune EncephalitisAuthors - Fan Zhang |
FITC荧光二抗？――EarthOx新型DyLight 488绿色荧光
中英文品名 品牌 货号 规格 详情 DyLight 488 AffiniPure Goat Anti-Mouse IgG（H+L） EarthOx E032210 ￥200/100μl ￥800/500μl 详情 DyLight 488
Anti-GFP/BrdU In Situ Immunostaining
Materials 24 well dishes Millicell 0.4 µm inserts (Millipore PICM01250) - coated with fibronectin Culture medium PBS Fixative: 4% paraformaldehyde in PBS (pH 7.6) Rabbit anti-GFP (Molecular Probes, A-11122) FITC-goat anti-rabbit
Immunohistochemistry using Anti-Ganglioside Antibodies
supernatant containing antiganglioside mAb overnight at 4°C. The time of incubation may range from 30 min. to overnight as determined by experience. 5. Wash with 1% BSA in PBS 4 times. 6. Incubate in FITC-conjugated goat anti-mouse IgM F(ab
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