相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
None
- 亚型:
IgG1, kappa
- 保存条件:
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
APC Fluorescent Dye
- 适应物种:
Human, Non-human primates
- 保质期:
详见产品包装
- 库存:
充足
- 宿主:
Mouse
- 应用范围:
FC
- 靶点:
CD62P
- 抗体英文名:
APC Anti-Human CD62P (AK4)
- 抗体名:
APC Anti-Human CD62P (AK4)
- 规格:
25tests/100tests
| 规格: | 25tests | 产品价格: | ¥1100.0 |
|---|---|---|---|
| 规格: | 100tests | 产品价格: | ¥2740.0 |
经过测试的应用
| Positive FC detected in | human peripheral blood platelets |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in 100 μl suspension |
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
APC-65164 targets CD62P in FC applications and shows reactivity with Human, Non-human primates samples.
| 经测试应用 | FC |
| 经测试反应性 | Human, Non-human primates |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | selectin P (granule membrane protein 140kDa, antigen CD62) |
| 别名 | AK4, CD62, CD62P, FLJ45155, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, SELP |
| 计算分子量 | 830 aa, 91 kDa |
| GenBank蛋白编号 | BC028067 |
| 基因名称 | CD62P |
| Gene ID (NCBI) | 6403 |
| RRID | AB_2883036 |
| 偶联类型 | APC Fluorescent Dye |
| 最大激发/发射波长 | 650 nm / 660 nm |
| 形式 | Liquid |
| 纯化方式 | The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
| UNIPROT ID | P16109 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Stimulation of Anti-HIV-1 Cytotoxic T Lymphocytes by Dendritic Cells
Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) in both primary and secondary T-cell responses. This may be related to their expression of high levels of MHC class I and II antigens (1 -4 ), costimulatory
Nature 三连发:竞争消除,有你没我,论癌细胞的「霸道行为」
结直肠癌 (CRC) 是胃肠道中常见的恶性肿瘤,其形成也是一个逐步发展的过程。前期研究数据表明,大多数结直肠癌起始于异常的腺窝,后逐渐演变成息肉,最终发展为结肠直肠癌,整个过程可长达 5 - 15 年。在内在分子机制层面,大多数结直肠癌是通过 WNT 通路的永久激活而启动的,而这种激活通常是发生在肠道干细胞中肿瘤抑制基因 APC 的突变之后。 APC 的突变可诱导肠内细胞增殖增加,防止细胞死亡并阻断分化,所有这些特征均可能有助于提高 APC 突变细胞的相对适应度,APC 突变的肠道干细胞及其后
Preparation of Synchronized Human Cell Extracts to Study Ubiquitination and Degradation
of Xenopus laevis eggs or synchronized human tissue culture cells. Here, we describe protocols to prepare extracts of synchronized human cells, and discuss experiments to use extracts for the biochemical analysis of APC/C-dependent ubiquitination.
技术资料暂无技术资料 索取技术资料










