- ￥1350 - 3000
- Proteintech
- 67586-1-Ig
- 2025年10月13日
- WB, ELISA
- Mouse
- human, rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human ATM protein
- 亚型：
IgG1
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human, rat
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Mouse
- 应用范围：
WB, ELISA
- 靶点：
ATM
- 抗体英文名：
ATM Monoclonal antibody
- 抗体名：
ATM Monoclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | HeLa cells, HSC-T6 cells, HEK-293 cells, HepG2 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:5000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
67586-1-Ig targets ATM in WB, IF, ELISA applications and shows reactivity with human, rat samples.
| 经测试应用 | WB, ELISA |
| 文献引用应用 | WB, IF |
| 经测试反应性 | human, rat |
| 文献引用反应性 | human, rat, pig |
| 免疫原 |
CatNo: Ag30001 Product name: Recombinant human ATM protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1059-1361 aa of BC137169 Sequence: SSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRKRFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKTQRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPKIIDCVGSDG |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | ataxia telangiectasia mutated |
| 别名 | 3E6F4, A T mutated, A-T mutated, EC:2.7.11.1, Serine-protein kinase ATM |
| 观测分子量 | 310-350 kDa |
| GenBank蛋白编号 | BC137169 |
| 基因名称 | ATM |
| Gene ID (NCBI) | 472 |
| RRID | AB_2882795 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q13315 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. It is involved in mitogenic signal transduction, meiotic recombination, detection of DNA damage, and cell cycle control.
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文献和实验| Species | Application | Title |
|---|---|---|
| human | WB | Food Chem Toxicol DON entry into the nucleus induces DNA damage, apoptosis and cycle arrest in GES-1 cellsAuthors - Silu Hou |
| rat | WB,IF | CNS Neurosci Ther Multiple sevoflurane exposures during mid-trimester induce neurotoxicity in the developing brain initiated by 15LO2-Mediated ferroptosisAuthors - Qian Jiang |
| human | WB | J Mol Med (Berl) High expression of BCAT1 sensitizes AML cells to PARP inhibitor by suppressing DNA damage responseAuthors - Jiajia Pan |
| pig | WB | Signal Transduct Target Ther In vivo evaluation of guide-free Cas9-induced safety risks in a pig modelAuthors - Weikai Ge |
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