USP12 多克隆抗体

Western Blot（WB）已验证样本:Mouse liver
免疫组织化学（IHC）已验证样本:Human tonsil

WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Polyclonal

IgG

Full length fusion protein

USP12

Deubiquitinating enzyme 12;OTTHUMP00000042337;UBH 1;UBH1;Ubiquitin carboxyl terminal hydrolase 12;Ubiquitin carboxyl-terminal hydrolase 12;Ubiquitin hydrolyzing enzyme 1 ;Ubiquitin specific peptidase 12;Ubiquitin specific processing protease 12;Ubiquitin specific protease 12 like 1;Ubiquitin thioesterase 12;Ubiquitin thiolesterase 12;Ubiquitin-hydrolyzing enzyme 1;Ubiquitin-specific-processing protease 12;UBP12;USP 12;Usp12;USP12L1抗体

O75317

43 kDa

Refer to figures

0.6 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cell Biology; Epigenetics and Nuclear Signaling

Unconjugated

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP12 (ubiquitin specific peptidase 12), also known as UBH1 or USP12L1, is a 370 amino acid protein belonging to the peptidase C19 family and the USP12/USP46 subfamily. Considered a deubiquitinating enzyme, it is suggested that USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have high activity. The gene encoding USP12 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.