GSK3 alpha 多克隆抗体

免疫组织化学（IHC）已验证样本:Human colon cancer,Human renal cancer

IHC 1:50-1:200

Polyclonal

IgG

Synthetic peptide of human GSK3A

GSK3A

DKFZp686D0638;Glycogen synthase kinase 3 alpha;Glycogen synthase kinase-3 alpha;GSK 3 alpha;GSK 3A;GSK-3 alpha;Gsk3a;GSK3A;GSK3alpha;Serine/threonine protein kinase GSK3A抗体

P49840

Cytosol,Mitochondrion,Other locations:apical dendrite,beta-catenin destruction complex,neuronal cell body,postsynapse,proximal dendrite

0.4 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Cell Biology; Cardiovascular; Signal Transduction; Stem Cells

Unconjugated

This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth.