PLAT 多克隆抗体

Western Blot（WB）已验证样本:231
免疫组织化学（IHC）已验证样本:Human lung cancer,Human esophagus cancer

WB 1:200-1:1000, IHC 1:50-1:200

Polyclonal

IgG

Synthetic peptide of human PLAT

PLAT

Alteplase;DKFZp686I03148;Plasminogen activator tissue;Plasminogen activator tissue type;PLAT;Reteplase;t PA;T Plasminogen Activator;t-PA;T-plasminogen activator;Tissue plasminogen activator (t PA);Tissue type plasminogen activator;Tissue-type plasminogen activator chain B;tPA;TPA;TPA1抗体

P00750

63kDa

Secreted>extracellular space.

0.4 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Cell Biology; Cardiovascular; Metabolism

Unconjugated

This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.