相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 亚型:
Rat IgG2a, κ
- 形态:
液体
- 保存条件:
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 克隆性:
Monoclonal
- 标记物:
PE/Cyanine5.5
- 适应物种:
Mouse
- 保质期:
12个月
- 目录编号:
E-AB-F1131I
- 级别:
科研
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 宿主:
Rat
- 应用范围:
FCM
- 抗体英文名:
PE/Cyanine5.5 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]_货号:E-AB-F1131I
- 抗体名:
PE/Cyanine5.5 Anti-Mouse CD279/PD-1 Antibody流式抗体[29F.1A12]_货号:E-AB-F1131I
- 规格:
100Tests/50Tests/100Tests×2
| 规格: | 100Tests | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50Tests | 产品价格: | ¥780.0 |
| 规格: | 100Tests×2 | 产品价格: | ¥2040.0 |

PE/Cyanine5.5 Anti-Mouse CD279/PD-1 抗体流式抗体[29F.1A12]产品名称:PE/Cyanine5.5 Anti-Mouse CD279/PD-1 Antibody[29F.1A12], 货号:E-AB-F1131I
| 产品描述: | CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. |
| Alternate Names | PD-1; Programmed Death-1; |
| Swissprot | Q02242 |
| Gene ID | 18566 |
| Clone No | 29F.1A12 |
| Host | Rat |
| Reactivity | Mouse |
| Application | FCM |
| 同种型 | Rat IgG2a, κ |
| 同种型 Control | PE/Cyanine5.5 Rat IgG2a, κ 同种型 Control[2A3] |
| Conjugation | PE/Cyanine5.5 |
| Conjugation Information | PE/Cyanine5.5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 690 nm (e.g., a 690/50 nm bandpass filter). |
| Spectrum | |
| 储存方法 缓冲 | Phosphate 缓冲ed solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| 储存方法 | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration date | 12个月 |
| Shipping | 冰袋 |

PE/Cyanine5.5 Anti-Mouse CD279/PD-1 抗体流式抗体[29F.1A12]labscience®拥有先进的单抗,多抗和流式抗体开发技术平台,提供8500+高品质 抗体, 适用于胞内和胞外蛋白的鉴定、定量和定位研究。抗体已在多种应用中得到验证,包含 流式细胞术(Flow Cytometry)、 免疫印迹(WB)、 免疫组化(IHC/ICC)、 免疫(共)沉淀(IP/Co-IP)、 免疫荧光(IF) 等实验。抗体产品涉及多种生命科学研究领域,包括肿瘤、免疫、心血管、细胞生物学、神经科学、表观遗传学等。Elabscience®始终致力于提高抗体的质量和种类,以保障并加快您的研究进程
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.PE/Cyanine5.5 Anti-Mouse CD279/PD-1 抗体流式抗体[29F.1A12]产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验a look from the following website just by clicking "Tyrosine Phosphorylation and Dimerization" http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-43F85YV-2&_user=1111158&_coverDate=06%2F29%2F2001&_rdoc=1&_fmt=full&_orig=search
(hematopoietic stem cells) 和CD279 (PD-1)。 · 将孵育好的样品加入到 1 ml 的 Strep-Tactin®TACS 琼脂糖层析柱上(柱子最大结合能力:1 x 108个细胞)。 · 当样品完全进入柱子后,加入 10 ml Buffer洗脱两次,就可以得到未结合的细胞了。后续使用流式细胞术检测富集的 NK 细胞。 (此处用到的试剂见文末) 结果与讨论 通过使用阴选将非目的细胞去除后,获得了高纯度的目的细胞群。实验用到了 Strep-Tactin®TACS 琼脂糖层析
STM:傅阳心、侯玉柱等发现放疗与免疫治疗的交汇点,兵家必争之地竟是这群细胞
究竟是哪些 T 细胞亚群发挥了上述作用,研究人员使用抗体清除 CD4 + 或 CD8+ T 细胞。结果发现,只有 CD8+ T 细胞的减少能够消除了放疗诱导的 Ter 细胞减少,这表明是 CD8 + 而不是 CD4+ T 细胞发挥作用。 图片来源:Sci. Transl. Med PD-L1 阻断治疗减少肿瘤诱导的 Ter 细胞积累 免疫疗法,包括 PD-L1 和 PD-1 阻断等,是有望治疗许多癌症的方法。PD-L1 阻断能够增强 CD8+ T 细胞的免疫功能,包括干扰素的产生和细胞毒活性的增强
技术资料暂无技术资料 索取技术资料





![Elab Bright Violet 421 仓鼠IgG2, Lambda 同型对照 [Ha4/8]](https://img1.dxycdn.com/p/s14/2025/0721/578/0004055067410717491.jpg!wh200)

