- 询价
- Cell Signaling Technology
- 3565
- USA
- 2025年08月16日
- F
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
CD10 (CB-CALLA) Mouse mAb
- 抗原：
CALLA cells
- 应用范围：
F
- 级别：
详见MSDS文件
- 库存：
大量
- 适应物种：
H
- 保质期：
详见说明书
- 供应商：
CST
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
400 ul (100 tests)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 400 ul (100 tests) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: F=Flow Cytometry
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| F | H | Endogenous | 100 | Mouse IgG1 |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | CD10 (CB-CALLA) Mouse mAb detects endogenous levels of CD10. |
| Source / Purification | Monoclonal antibody is produced by immunizing BALB/c mice with CALLA cells. Flow Cytometry
Flow cytometric analysis of whole blood, using CD10 (CB-CALLA) Mouse mAb. |
| Background | CD10 (CALLA or neprilysin) was identified as a marker for leukemic cells in children with acute lymphoblastic leukemia and belongs to a family of exoenzymes that include aminopeptidase A, N and dipeptidylpeptidase IV (1-2). CD10 is a transmembrane type II molecule and functions as a metallo-peptidase requiring zinc. Specifically, CD10 cleaves 1-3 amino-terminal amino acids from peptides with a preference for neutral amino acids (valine, iso-leucine, phenylalanine, leucine or alanine) (2). The CD10 antigen is expressed by immature and by germinal center B cells, by granulocytes and by acute B-cell lymphoblastic leukemia cells. Therefore, CD10 appears to be involved in late stage regulation of hematopoietic cells (3). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验CD10 分子 CD10 常用单克隆抗体或代号：J5；(CALlA) 主要表达细胞：Pre-B，CAI。L，G[B] 分子质量(kDa)和结构：gp100(Ⅱ型膜分子) 功 能：为结合锌的金属蛋白酶，调节B细胞生长和增殖 CD10 Aka Common Acute Lymphoblastic Leukemia Antigen (CALLA), neutral endopeptidase 24.11, neprilysin
(adjust pH to 7.8 with Binding buffer; red color) to the Protein A column.Mouse antibodies of the IgG1 subclass do not have a high affinity for protein A. Purification on protein A beads using standard conditions will yield approximately 1/10
Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers
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