Cimpuciclib,2202767-78-8

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Cimpuciclib

CAS No. : 2202767-78-8

MCE 国际站：Cimpuciclib

产品活性：Cimpuciclib 是一种选择性的 CDK4 抑制剂 (IC₅₀: 0.49 nM)，具有抗肿瘤活性。

研究领域：Cell Cycle/DNA Damage

作用靶点：CDK

In Vitro: Cimpuciclib (example 63, 141.2 nM, 6 days) inhibits proliferation in colo205 cells.

In Vivo: Cimpuciclib (example 63, 50 mg/kg, oral gavage, twice a week) inhibits tumor growth in colo205 tumor-bearing mice.
Cimpuciclib (5 mg/kg for rats, 50 mg/kg for colo205 tumor-bearing mice, oral administration) shows slow metabolic rate and maintains high concentration in the plasma.

相关产品：Palbociclib  |  Abemaciclib  |  Ro-3306  |  Ribociclib  |  Dinaciclib  |  GSK3326595  |  THZ1  |  Flavopiridol  |  SR-4835  |  (R)-Roscovitine  |  THZ531  |  AZD4573  |  SY-5609  |  Kenpaullone  |  Wogonin  |  SNS-032  |  GSK 3 Inhibitor IX  |  Cirtuvivint  |  NVP-2  |  Toyocamycin  |  Fadraciclib  |  Simurosertib  |  AT7519  |  OTS964 hydrochloride  |  JNJ-7706621  |  KB-0742 dihydrochloride  |  BSJ-4-116

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds