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- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
14362-31-3
- 规格：
10 mM * 1 mL/100 mg/200 mg/500 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥660.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥600.0 |
| 规格： | 200 mg | 产品价格： | ￥900.0 |
| 规格： | 500 mg | 产品价格： | ￥1900.0 |
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Chlorcyclizine hydrochloride
CAS No. : 14362-31-3
MCE 国际站：Chlorcyclizine hydrochloride
产品活性：Chlorcyclizine hydrochloride 是一种组胺 H1 拮抗剂。
研究领域：GPCR/G Protein | Neuronal Signaling | Immunology/Inflammation
作用靶点：Histamine Receptor
In Vivo: Pregnant rats administered 30, 60, and 90mg/kg Chlorcyclizine during the sensitive period for palate development survived until scheduled sacrifice on Gestation Days (GDs) 17 or 21. The rats administered 60 or 90mg/kg Chlorcyclizine have transient adverse clinical signs (chromorhinorrhea, red peri-oral substance, urogenital staining, and scant stool) and a concomitant body weight loss of 7% and 11%, respectively, over the dosing interval. Rats administered 30mg/kg Chlorcyclizine do not exhibit any adverse clinical signs, but do not gain weight over the dose interval as would be expected during pregnancy. Based on the testing facility’s historical control database (16 studies, n=380). pregnant rats typically gain about 6% body weight from GDs 12 to 15.
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