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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide within mouse TLR7 aa 597-640
- 亚型:
IgG
- 形态:
Liquid
- 克隆性:
Rabbit polyclonal Antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat
- 库存:
现货
- 供应商:
华安生物
- 宿主:
Rabbit
- 应用范围:
WB, IHC-P
- 浓度:
1 mg/mL.
- 抗体名:
TLR7
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1125.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥1875.0 |
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文献和实验Development of TLR7/8 Small RNA Antagonists
Toll-like receptors (TLRs) expressed by innate immune cells recognize a spectrum of microbial structures. Recent studies have provided convincing evidence that TLR7 and TLR8 play a key role in sensing viral RNAs. Under certain conditions
Viral single-stranded (ss) RNA is the natural ligand for TLR7 and TLR8. Synthetic ssRNA has been shown to act as a ligand for TLR7 and TLR8. We have previously reported a novel RNA structure, referred to as stabilized immune modulatory RNA
Toll-Like Receptor-Dependent Immune Complex Activation of B Cells and Dendritic Cells
-like receptor 7 (TLR7) in the activation of the corresponding autoantibody producing B cells. Importantly, TLR9/TLR7-deficiency results in the inability of autoreactive B cells to proliferate in response to DNA/RNA-associated autoantigens in vitro, and in marked
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